Publication: Late presentation into care of HIV disease and its associated factors in Asia: Results of TAHOD
Issued Date
2016-03-01
Resource Type
ISSN
19318405
08892229
08892229
Other identifier(s)
2-s2.0-84960121715
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
AIDS Research and Human Retroviruses. Vol.32, No.3 (2016), 255-261
Suggested Citation
Su Jin Jeong, Claire Italiano, Romanee Chaiwarith, Oon Tek Ng, Sasheela Vanar, Awachana Jiamsakul, Vonthanak Saphonn, Kinh Van Nguyen, Sasisopin Kiertiburanakul, Man Po Lee, Tuti Parwati Merati, Thuy Thanh Pham, Evy Yunihastuti, Rossana Ditangco, Nagalingeswaran Kumarasamy, Fujie Zhang, Wingwai Wong, Benedict L.H. Sim, Sanjay Pujari, Pacharee Kantipong, Praphan Phanuphak, Winai Ratanasuwan, Shinichi Oka, Mahiran Mustafa, Nicolas Durier, Jun Yong Choi Late presentation into care of HIV disease and its associated factors in Asia: Results of TAHOD. AIDS Research and Human Retroviruses. Vol.32, No.3 (2016), 255-261. doi:10.1089/aid.2015.0058 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/40842
Research Projects
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Title
Late presentation into care of HIV disease and its associated factors in Asia: Results of TAHOD
Author(s)
Su Jin Jeong
Claire Italiano
Romanee Chaiwarith
Oon Tek Ng
Sasheela Vanar
Awachana Jiamsakul
Vonthanak Saphonn
Kinh Van Nguyen
Sasisopin Kiertiburanakul
Man Po Lee
Tuti Parwati Merati
Thuy Thanh Pham
Evy Yunihastuti
Rossana Ditangco
Nagalingeswaran Kumarasamy
Fujie Zhang
Wingwai Wong
Benedict L.H. Sim
Sanjay Pujari
Pacharee Kantipong
Praphan Phanuphak
Winai Ratanasuwan
Shinichi Oka
Mahiran Mustafa
Nicolas Durier
Jun Yong Choi
Claire Italiano
Romanee Chaiwarith
Oon Tek Ng
Sasheela Vanar
Awachana Jiamsakul
Vonthanak Saphonn
Kinh Van Nguyen
Sasisopin Kiertiburanakul
Man Po Lee
Tuti Parwati Merati
Thuy Thanh Pham
Evy Yunihastuti
Rossana Ditangco
Nagalingeswaran Kumarasamy
Fujie Zhang
Wingwai Wong
Benedict L.H. Sim
Sanjay Pujari
Pacharee Kantipong
Praphan Phanuphak
Winai Ratanasuwan
Shinichi Oka
Mahiran Mustafa
Nicolas Durier
Jun Yong Choi
Other Contributor(s)
Yonsei University
University of Malaya Medical Centre
Chiang Mai University
Tan Tock Seng Hospital
University of New South Wales (UNSW) Australia
University of Health Sciences
National Hospital for Tropical Diseases
Mahidol University
Queen Elizabeth Hospital Hong Kong
Universitas Udayana
Bach Mai Hospital
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
Gokila
VHS Medical Centre India
Beijing Ditan Hospital
Veterans General Hospital-Taipei
Hospital Sungai Buloh
Institute of Infectious Diseases
Chiangrai Prachanukroh Hospital
The HIV Netherlands Australia Thailand Research Collaboration
National Center for Global Health and Medicine
Hospital Raja Perempuan Zainab II
amfAR - The Foundation for AIDS Research
University of Malaya Medical Centre
Chiang Mai University
Tan Tock Seng Hospital
University of New South Wales (UNSW) Australia
University of Health Sciences
National Hospital for Tropical Diseases
Mahidol University
Queen Elizabeth Hospital Hong Kong
Universitas Udayana
Bach Mai Hospital
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
Gokila
VHS Medical Centre India
Beijing Ditan Hospital
Veterans General Hospital-Taipei
Hospital Sungai Buloh
Institute of Infectious Diseases
Chiangrai Prachanukroh Hospital
The HIV Netherlands Australia Thailand Research Collaboration
National Center for Global Health and Medicine
Hospital Raja Perempuan Zainab II
amfAR - The Foundation for AIDS Research
Abstract
© Mary Ann Liebert, Inc. 2016. Many HIV-infected individuals do not enter health care until late in the infection course. Despite encouraging earlier testing, this situation has continued for several years. We investigated the prevalence of late presenters and factors associated with late presentation among HIV-infected patients in an Asian regional cohort. This cohort study included HIV-infected patients with their first positive HIV test during 2003-2012 and CD4 count and clinical status data within 3 months of that test. Factors associated with late presentation into care (CD4 count <200 cells/μl or an AIDS-defining event within ±3 months of first positive HIV test) were analyzed in a random effects logistic regression model. Among 3,744 patients, 2,681 (72%) were late presenters. In the multivariable model, older patients were more likely to be late presenters than younger (≤30 years) patients [31-40, 41-50, and ≥51 years: odds ratio (OR) = 1.57, 95% confidence interval (CI) 1.31-1.88; OR = 2.01, 95% CI 1.58-2.56; and OR = 1.69, 95% CI 1.23-2.31, respectively; all p ≤ 0.001]. Injecting drug users (IDU) were more likely (OR = 2.15, 95% CI 1.42-3.27, p < 0.001) and those with homosexual HIV exposure were less likely (OR = 0.45, 95% CI 0.35-0.58, p < 0.001) to be late presenters compared to those with heterosexual HIV exposure. Females were less likely to be late presenters (OR = 0.44, 95% CI 0.36-0.53, p < 0.001). The year of first positive HIV test was not associated with late presentation. Efforts to reduce the patients who first seek HIV care at the late stage are needed. The identified risk factors associated with late presentation should be utilized in formulating targeted public health intervention to improve earlier entry into HIV care.