Publication:
The mosquito larvicidal activity of 130 KDA delta-endotoxin of Bacillus thuringiensis var. israelensis resides in the 72 KDA amino-terminal fragment

Issued Date

1988-05-31

Resource Type

Article

ISSN

10902104
0006291X

DOI

10.1016/S0006-291X(88)81221-X

Other identifier(s)

2-s2.0-0023914794

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Biochemical and Biophysical Research Communications. Vol.153, No.1 (1988), 294-300

Suggested Citation

Manu Pao-intara, Chanan Angsuthanasombat, Sakol Panyim The mosquito larvicidal activity of 130 KDA delta-endotoxin of Bacillus thuringiensis var. israelensis resides in the 72 KDA amino-terminal fragment. Biochemical and Biophysical Research Communications. Vol.153, No.1 (1988), 294-300. doi:10.1016/S0006-291X(88)81221-X Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/15492

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Title

The mosquito larvicidal activity of 130 KDA delta-endotoxin of Bacillus thuringiensis var. israelensis resides in the 72 KDA amino-terminal fragment

Author(s)

Manu Pao-intara
 Chanan Angsuthanasombat
 Sakol Panyim

Other Contributor(s)

Mahidol University

Abstract

Bacillus thuringiensis var. israelensis produces 130 kDa delta-endotoxin which is highly toxic to mosquito-larvae. The mosquito-larvicidal activity was delineated by sequential deletions from ends of the 1136 amino acids delta-endotoxin. A maximum of 459 amino acids could be removed from the carboxy-terminal of the toxin without a significant loss of the larvicidal activity. However, no more than 38 amino acids could be deleted from the amino-terminal without losing the toxicity. The truncated peptide of 72. kDa exhibited similar toxicity to the 130 kDa toxin and was between 39 th and 677 th amino acids. © 1988 Academic Press, Inc.

Keyword(s)

Biochemistry, Genetics and Molecular Biology

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URI

https://repository.li.mahidol.ac.th/handle/123456789/15492

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Scopus 1969-1990