Publication: Agreement between colposcopic diagnosis and cervical pathology: Siriraj hospital experience
Issued Date
2014-01-01
Resource Type
ISSN
2476762X
15137368
15137368
Other identifier(s)
2-s2.0-84894067541
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asian Pacific Journal of Cancer Prevention. Vol.15, No.1 (2014), 423-426
Suggested Citation
Molpen Tatiyachonwiphut, Atthapon Jaishuen, Suthi Sangkarat, Somsak Laiwejpithaya, Weerasak Wongtiraporn, Perapong Inthasorn, Boonlert Viriyapak, Malee Warnnissorn Agreement between colposcopic diagnosis and cervical pathology: Siriraj hospital experience. Asian Pacific Journal of Cancer Prevention. Vol.15, No.1 (2014), 423-426. doi:10.7314/APJCP.2014.15.1.423 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/33366
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Agreement between colposcopic diagnosis and cervical pathology: Siriraj hospital experience
Other Contributor(s)
Abstract
Aim: To evaluate the agreement between colposcopic diagnosis and cervical pathology a retrospective chart review was performed. Materials and Methods: This study included 437 patients who underwent colposcopy and cervical biopsy or conization at Siriraj Hospital from October 2010 - December 2012. The patient clinical characteristics, cervical cytology results, colposcopic diagnoses, cervical pathology results were recorded and correlations between variables were analyzed. Results: Agreement of colposcopic diagnosis and cervical pathology was matched in 253 patients (57.9%). The strength of agreement with weighted Kappa statistic was 0.494 (p<0.001). Colposcopic diagnoses more often overestimated (31.1%) than underestimated (11%) the cervical pathology. Agreement of colposcopic diagnosis and cervical pathology within 1 grade was found in 411 patients (94.1%). Positive predictive value (PPV) of high grade colposcopy or more was 75.5%, whereas the negative predictive value (NPV) of insignificant and low grade colposcopy was 83.8%. False positives of high grade colposcopy or more were 21%. False negatives of insignificant or low grade colposcopy were 19.1%. Conclusions: Strength of agreement between colposcopic diagnosis and cervical pathology was found to be only moderate. A biopsy at colposcopy should be performed at a gold standard level to detect high grade lesions.