Publication: Mutagenicity of extracts from ceylon cinnamon in the rec assay
1
Issued Date
1984-01-01
Resource Type
ISSN
02786915
Other identifier(s)
2-s2.0-0021354297
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Food and Chemical Toxicology. Vol.22, No.2 (1984), 109-112
Suggested Citation
M. Ungsurungsie, C. Paovalo, A. Noonai Mutagenicity of extracts from ceylon cinnamon in the rec assay. Food and Chemical Toxicology. Vol.22, No.2 (1984), 109-112. doi:10.1016/0278-6915(84)90089-9 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/30557
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Mutagenicity of extracts from ceylon cinnamon in the rec assay
Author(s)
Other Contributor(s)
Abstract
The extraction of about 1.9 kg of Ceylon cinnamon (Cinnamomum zeylanicum Nees) with 10 litres each of petroleum ether, chloroform and ethanol in a Soxhlet apparatus produced extracts weighing 76, 28 and 270 g respectively for the three solvents. In the preliminary test the ethanol extract showed no mutagenic activity. However, both the petroleum ether and the chloroform extracts showed mutagenicity when tested in the rec assay using Bacillus subtilis strains H17 (rec+) and M45 (rec-). When these extracts were studied quantitatively by the liquid and spore rec-assay methods, the minimum inhibitory concentrations of the extracts against strain H17 were higher than those against strain M45. However, in the presence of the liver S-9 mix, the minimum inhibitory concentrations of the petroleum ether and chloroform extracts against both strains of B. subtilis were equal, indicating that the mutagenicity of the extracts had been inactivated. © 1984.