Publication:
Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy

1

Issued Date

2018-12-01

Resource Type

Review

ISSN

15737217
01676806

DOI

10.1007/s10549-018-4937-1

Other identifier(s)

2-s2.0-85053429342

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Breast Cancer Research and Treatment. Vol.172, No.3 (2018), 523-537

Suggested Citation

Walter P. Weber, Martin Haug, Christian Kurzeder, Vesna Bjelic-Radisic, Rupert Koller, Roland Reitsamer, Florian Fitzal, Jorge Biazus, Fabricio Brenelli, Cicero Urban, Régis Resende Paulinelli, Jens Uwe Blohmer, Jörg Heil, Jürgen Hoffmann, Zoltan Matrai, Giuseppe Catanuto, Viviana Galimberti, Oreste Gentilini, Mitchel Barry, Tal Hadar, Tanir M. Allweis, Oded Olsha, Maria João Cardoso, Pedro F. Gouveia, Isabel T. Rubio, Jana de Boniface, Tor Svensjö, Susanne Bucher, Peter Dubsky, Jian Farhadi, Mathias K. Fehr, Ilario Fulco, Ursula Ganz-Blättler, Andreas Günthert, Yves Harder, Nik Hauser, Elisabeth A. Kappos, Michael Knauer, Julia Landin, Robert Mechera, Francesco Meani, Giacomo Montagna, Mathilde Ritter, Ramon Saccilotto, Fabienne D. Schwab, Daniel Steffens, Christoph Tausch, Jasmin Zeindler, Savas D. Soysal, Visnu Lohsiriwat, Tibor Kovacs, Anne Tansley, Lynda Wyld, Laszlo Romics, Mahmoud El-Tamer, Andrea L. Pusic, Virgilio Sacchini, Michael Gnant Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy. Breast Cancer Research and Treatment. Vol.172, No.3 (2018), 523-537. doi:10.1007/s10549-018-4937-1 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/44993

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy

Author(s)

Walter P. Weber
 Martin Haug
 Christian Kurzeder
 Vesna Bjelic-Radisic
 Rupert Koller
 Roland Reitsamer
 Florian Fitzal
 Jorge Biazus
 Fabricio Brenelli
 Cicero Urban
 Régis Resende Paulinelli
 Jens Uwe Blohmer
 Jörg Heil
 Jürgen Hoffmann
 Zoltan Matrai
 Giuseppe Catanuto
 Viviana Galimberti
 Oreste Gentilini
 Mitchel Barry
 Tal Hadar
 Tanir M. Allweis
 Oded Olsha
 Maria João Cardoso
 Pedro F. Gouveia
 Isabel T. Rubio
 Jana de Boniface
 Tor Svensjö
 Susanne Bucher
 Peter Dubsky
 Jian Farhadi
 Mathias K. Fehr
 Ilario Fulco
 Ursula Ganz-Blättler
 Andreas Günthert
 Yves Harder
 Nik Hauser
 Elisabeth A. Kappos
 Michael Knauer
 Julia Landin
 Robert Mechera
 Francesco Meani
 Giacomo Montagna
 Mathilde Ritter
 Ramon Saccilotto
 Fabienne D. Schwab
 Daniel Steffens
 Christoph Tausch
 Jasmin Zeindler
 Savas D. Soysal
 Visnu Lohsiriwat
 Tibor Kovacs
 Anne Tansley
 Lynda Wyld
 Laszlo Romics
 Mahmoud El-Tamer
 Andrea L. Pusic
 Virgilio Sacchini
 Michael Gnant

Other Contributor(s)

New Victoria Hospital, Glasgow
 Champalimaud Foundation
 Universidade Positivo
 Azienda Ospedaliera Cannizzaro
 IRCCS San Raffaele Scientific Institute
 Klinik St. Anna
 Uniklinik Düsseldorf
 Ente Ospedaliero Cantonale
 Universidad de Navarra
 Kaplan Medical Center Israel
 Kantonsspital Luzern
 Országos Onkológiai Intézet Budapest
 Istituto Europeo di Oncologia
 Universidade Estadual de Campinas
 Universitätsspital Basel
 Universität St. Gallen
 Charité – Universitätsmedizin Berlin
 Kristianstad Central Hospital
 Universitat Basel
 Centre Hospitalier Universitaire Vaudois
 Universität Witten/Herdecke
 Mater Misericordiae University Hospital
 Brigham and Women's Hospital
 Hospital de Clinicas de Porto Alegre
 Karolinska Institutet
 Medizinische Universitat Wien
 Klinik Hirslanden
 Faculty of Medicine, Siriraj Hospital, Mahidol University
 Memorial Sloan-Kettering Cancer Center
 Royal Liverpool and Broadgreen University Hospitals NHS Trust
 Hebrew University of Jerusalem
 Medizinische Universität Graz
 Guy's and St Thomas' NHS Foundation Trust
 Universitat Salzburg
 University of Sheffield
 Capio S:t Görans Sjukhus
 Wiener Krakenanstaltenverbund
 Breast Center Zürich
 Breast Center St. Gallen
 University of Heidelberg
 Araújo Jorge Hospital

Abstract

© 2018, The Author(s). Purpose: Indications for nipple-sparing mastectomy (NSM) have broadened to include the risk reducing setting and locally advanced tumors, which resulted in a dramatic increase in the use of NSM. The Oncoplastic Breast Consortium consensus conference on NSM and immediate reconstruction was held to address a variety of questions in clinical practice and research based on published evidence and expert panel opinion. Methods: The panel consisted of 44 breast surgeons from 14 countries across four continents with a background in gynecology, general or reconstructive surgery and a practice dedicated to breast cancer, as well as a patient advocate. Panelists presented evidence summaries relating to each topic for debate during the in-person consensus conference. The iterative process in question development, voting, and wording of the recommendations followed the modified Delphi methodology. Results: Consensus recommendations were reached in 35, majority recommendations in 24, and no recommendations in the remaining 12 questions. The panel acknowledged the need for standardization of various aspects of NSM and immediate reconstruction. It endorsed several oncological contraindications to the preservation of the skin and nipple. Furthermore, it recommended inclusion of patients in prospective registries and routine assessment of patient-reported outcomes. Considerable heterogeneity in breast reconstruction practice became obvious during the conference. Conclusions: In case of conflicting or missing evidence to guide treatment, the consensus conference revealed substantial disagreement in expert panel opinion, which, among others, supports the need for a randomized trial to evaluate the safest and most efficacious reconstruction techniques.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/44993

Collections

Scopus 2018