Southeast Asian Journal of Tropical Medicine and Public Health. Vol.29, No.4 (1998), 758-762
Suggested Citation
Chalobon Yoosook A sensitive assay for anti-HIV-1 drug discovery in a biological safety level-2 laboratory. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.29, No.4 (1998), 758-762. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/18438
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A sensitive assay for anti-HIV-1 drug discovery in a biological safety level-2 laboratory
Studies involving infectious, wild type HIV-1 must be performed under strict BSL-3 practice. We have employed a defective ΔTatRevMC99 and cloned 1A2 line, ie, mutated HIV-1 and Tat/Rev transfected cells to verify anti-HIV-1 activity in a BSL-2 laboratory. A number of extracts from various parts of 11 species of plants were studied. Results were correlated with those of an anti-HIV-1 reverse transcriptase (RT) assay.
