Publication: Patterns of Single Photon Emission Tomography (SPECT) among patients with dementia in the Memory Clinic at Siriraj Hospital
Issued Date
2006-11-01
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ISSN
01252208
01252208
01252208
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2-s2.0-33845472658
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.89, No.11 (2006), 1829-1834
Suggested Citation
Arpas Nako, Sasitorn Siritho, Wattanachai Chotinaiwattarakul, Vacharin Ratanamart, Suthipol Udompunthuruk, Piyanuj Jamjumrus, Vorapun Senanarong Patterns of Single Photon Emission Tomography (SPECT) among patients with dementia in the Memory Clinic at Siriraj Hospital. Journal of the Medical Association of Thailand. Vol.89, No.11 (2006), 1829-1834. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/23490
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Title
Patterns of Single Photon Emission Tomography (SPECT) among patients with dementia in the Memory Clinic at Siriraj Hospital
Other Contributor(s)
Abstract
Objective: The authors hypothesized that there is a pattern difference in cerebral perfusion of the 99-Technitium L, L-ethyl cysteinate dimer Single Photon Emission Computer Tomography (99-Tc ECD SPECT) between mild and moderate to severe dementia. Material and Method: The authors reported a retrospective study in the Memory Clinic, Siriraj Hospital between January 2001 and October 2003 including only patients with Alzheimer's disease, vascular dementia, and mixed dementia. Clinical dementia rating (CDR) was used to document dementia severity. Patterns of hypoperfusion were classified into no definite hypoperfusion, regional hypoperfusion, and diffused hypoperfusion. Results: One hundred and seven patients were included in the present study. Only mean Thai Mental State Examination (TMSE) score was different between the two groups. There was no significant correlation between pattern of hypoperfusion in brain SPECT and severity of dementia. Conclusion: The authors cannot demonstrate the pattern of hypoperfusion of 99-Tc ECD SPECT among patients' difference in dementia severity.