Publication: Leptin concentration in relation to body mass index (BMI) and hematological measurements in Thai obese and overweight subjects
Issued Date
2000-12-01
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ISSN
01251562
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2-s2.0-0034574870
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.4 (2000), 787-794
Suggested Citation
Rungsunn Tungtrongchitr, Praneet Pongpaew, Benjaluck Phonrat, Siriwan Tribunyatkul, Duangkamol Viroonudomphol, Venus Supawan, Pornrutsami Jintaridhi, Ariya Lertchavanakul, Niyomsri Vudhivai, Frank Peter Schelp Leptin concentration in relation to body mass index (BMI) and hematological measurements in Thai obese and overweight subjects. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.4 (2000), 787-794. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/26101
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Title
Leptin concentration in relation to body mass index (BMI) and hematological measurements in Thai obese and overweight subjects
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Abstract
The weight, height and body mass index (BMI), including waist/hip ratio, serum leptin and hematological parameters of 48 male and 166 female overweight (BMI ≥ 25.00) Thai volunteers who came for a physical check-up at the Out-patient Department, General Practice Section, Rajvithi Hospital, Bangkok during the period March-October 1998, were investigated. There were statistically significantly higher levels of serum leptin, mean corpuscular mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) in the overweight than in the control subjects. The median serum leptin concentration in overweight subjects was 19.6 (2.0-60.0 ng/ml) compared with 9.0 (range 1.0-30.0 ng/ml) in the control subjects (p < 0.001). The medians of leptin in overweight and obese males were significantly higher than those of overweight and obese females. 66.7% (32 out of 48) of overweight and obese males were found to have elevated leptin levels, while 87.3% (145 out of 166) were found in overweight and obese females. Anemia was found in 18.7% of female overweight and obese subjects, using hemoglobin as an indicator. Significant associations were found between weight, height, BMI, waist, hip, waist/hip ratio, hemoglobin, hematocrit, and serum leptin in both male and female overweight subjects. A negative correlation was found between serum leptin and hemoglobin, and hematocrit in both overweight and obese subjects.