Publication: An antimalarial stilbene from Artocarpus integer
Issued Date
2000-06-01
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ISSN
00319422
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2-s2.0-0034733502
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Mahidol University
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SCOPUS
Bibliographic Citation
Phytochemistry. Vol.54, No.4 (2000), 415-417
Suggested Citation
Choosak Boonlaksiri, Worrapoj Oonanant, Palangpon Kongsaeree, Prasat Kittakoop, Morakot Tanticharoen, Yodhathai Thebtaranonth An antimalarial stilbene from Artocarpus integer. Phytochemistry. Vol.54, No.4 (2000), 415-417. doi:10.1016/S0031-9422(00)00074-1 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/25797
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Title
An antimalarial stilbene from Artocarpus integer
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Abstract
Antimalarial activity-guided study of the aerial parts of Artocarpus integer led to the isolation of the prenylated stilbene, trans-4-(3-methyl-E- but-1-enyl)-3,5,2',4'- tetrahydroxystilbene with an EC50of 1.7 μg/ml against Plasmodium falciparum in culture. The known stilbenes, trans-4- isopentenyl-3,5,2',4'-tetrahydroxystilbene and 4-methoxy-2,2-dimethyl-6-(2- (2,4-dihydroxy)phenyl-trans-ethenyl)chromene, were also isolated. Structures of these compounds were deduced on the basis of their spectral data. (C) 2000 Elsevier Science Ltd.
