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The efficacy of anti-malaria drugs against Plasmodium vivax on the Thailand-Myanmar border

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dc.contributor.authorTakeshi Yodaen_US
dc.contributor.authorYasuyuki Rakueen_US
dc.contributor.authorTsutomu Mizotaen_US
dc.contributor.authorSornchai Looareesuwanen_US
dc.contributor.otherNagasaki Universityen_US
dc.contributor.otherToda Central General Hospitalen_US
dc.contributor.otherTulane Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-06-21T08:30:03Z
dc.date.available2018-06-21T08:30:03Z
dc.date.issued2005-03-01en_US
dc.description.abstractThe susceptibility of 20 isolates of Plasmodium vivax obtained in the area of the Thailand-Myanmar border to seven antimalarial drugs was evaluated using the schizont maturation inhibition technique. The geometric mean 50% inhibition concentration (IC 50) values were quinine=308 ng/ml, amodiaquine=14 ng/ml, chloroquine=50 ng/ml, mefloquine=127 ng/ml, sulfadoxine/pyrimethamine (80:1) =800/10 ng/ml, pyrimethamine=8 ng/ml, and artesunate=0.5 ng/ml. Compared with P. falciparum in this area, P. vivax was more sensitive to chloroquine and artesunate, equally sensitive to quinine, and more resistant to mefloquine.en_US
dc.identifier.citationJournal of Tokyo Medical University. Vol.63, No.2 (2005), 140-143en_US
dc.identifier.issn00408905en_US
dc.identifier.other2-s2.0-18244391452en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/17058
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=18244391452&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleThe efficacy of anti-malaria drugs against Plasmodium vivax on the Thailand-Myanmar borderen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=18244391452&origin=inwarden_US

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