Publication:
Optimal design strategies for relative potency using the two-parameter log-logistic model

Issued Date

2016-04-13

Resource Type

Article

ISSN

15741699

DOI

10.3233/MAS-150357

Other identifier(s)

2-s2.0-84965020930

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Model Assisted Statistics and Applications. Vol.11, No.2 (2016), 109-123

Suggested Citation

Pattaraporn Tusto, Timothy E. O'Brien, Montip Tiensuwan Optimal design strategies for relative potency using the two-parameter log-logistic model. Model Assisted Statistics and Applications. Vol.11, No.2 (2016), 109-123. doi:10.3233/MAS-150357 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/40935

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Title

Optimal design strategies for relative potency using the two-parameter log-logistic model

Author(s)

Pattaraporn Tusto
 Timothy E. O'Brien
 Montip Tiensuwan

Other Contributor(s)

Mahidol University
 Loyola University of Chicago
 South Carolina Commission on Higher Education

Abstract

© 2016 - IOS Press and the authors. All rights reserved. In this paper, we focus on the D- and Ds-optimal designs for two-parameter log-logistic (LL2) relative potency model where the response variables are normal and binomial distributions. The D- and Ds-optimal designs are obtained by using D-optimal design and nesting strategy criterions, respectively. Furthermore, the general equivalence theorems is used to guarantee the D- and Ds-optimal designs. The results show that we obtain four support points for D-optimal designs and two support points for Ds-optimal designs.

Keyword(s)

Mathematics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/40935

Collections

Scopus 2016-2017