Publication:
F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system

Issued Date

2016-01-01

Resource Type

Article

ISSN

14770520

DOI

10.1039/C6OB02255C

Other identifier(s)

2-s2.0-84998704813

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Organic and Biomolecular Chemistry. Vol.14, No.46 (2016), 11002-11012

Suggested Citation

Kulvadee Dolsophon, Jakapun Soponpong, Jittra Kornsakulkarn, Chawanee Thongpanchang, Samran Prabpai, Palangpon Kongsaeree, Tienthong Thongpanchang F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system. Organic and Biomolecular Chemistry. Vol.14, No.46 (2016), 11002-11012. doi:10.1039/C6OB02255C Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/43220

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Title

F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system

Author(s)

Kulvadee Dolsophon
 Jakapun Soponpong
 Jittra Kornsakulkarn
 Chawanee Thongpanchang
 Samran Prabpai
 Palangpon Kongsaeree
 Tienthong Thongpanchang

Other Contributor(s)

Mahidol University
 Thailand National Center for Genetic Engineering and Biotechnology

Abstract

© The Royal Society of Chemistry. F-THENA is designed as an alternative fluorine-containing chiral derivatizing agent (CDA). The fluorine atom functions exclusively as a reporter which can directly sense an anisotropic effect from an aromatic substituent of a chiral alcohol. In combination with chemical shift differences from both19F NMR and1H NMR, the F-THENA method can successfully be used for determining the absolute configuration of chiral secondary aromatic alcohols with a self-validating system.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/43220

Collections

Scopus 2016-2017