Publication:
Type 1 diabetes management and outcomes: A multicenter study in Thailand

Issued Date

2021-04-01

Resource Type

Article

ISSN

20401124
20401116

DOI

10.1111/jdi.13390

Other identifier(s)

2-s2.0-85103805010

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Diabetes Investigation. Vol.12, No.4 (2021), 516-526

Suggested Citation

Prapai Dejkhamron, Jeerunda Santiprabhob, Supawadee Likitmaskul, Chaicharn Deerochanawong, Petch Rawdaree, Thipaporn Tharavanij, Sirimon Reutrakul, Chawkaew Kongkanka, Chittiwat Suprasongsin, Nawaporn Numbenjapon, Taninee Sahakitrungruang, Raweewan Lertwattanarak, Pontipa Engkakul, Apiradee Sriwijitkamol, Manassawee Korwutthikulrangsri, Rattana Leelawattana, Mattabhorn Phimphilai, Somkiat Potisat, Panthep Khananuraksa, Cherdchai Nopmaneejumruslers, Wannee Nitiyanant Type 1 diabetes management and outcomes: A multicenter study in Thailand. Journal of Diabetes Investigation. Vol.12, No.4 (2021), 516-526. doi:10.1111/jdi.13390 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/78306

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Title

Type 1 diabetes management and outcomes: A multicenter study in Thailand

Author(s)

Prapai Dejkhamron
 Jeerunda Santiprabhob
 Supawadee Likitmaskul
 Chaicharn Deerochanawong
 Petch Rawdaree
 Thipaporn Tharavanij
 Sirimon Reutrakul
 Chawkaew Kongkanka
 Chittiwat Suprasongsin
 Nawaporn Numbenjapon
 Taninee Sahakitrungruang
 Raweewan Lertwattanarak
 Pontipa Engkakul
 Apiradee Sriwijitkamol
 Manassawee Korwutthikulrangsri
 Rattana Leelawattana
 Mattabhorn Phimphilai
 Somkiat Potisat
 Panthep Khananuraksa
 Cherdchai Nopmaneejumruslers
 Wannee Nitiyanant

Other Contributor(s)

Siriraj Hospital
 National Health Security Office
 Faculty of Medicine, Chiang Mai University
 Faculty of Medicine, Prince of Songkia University
 Rangsit University
 Vajira Hospital
 Faculty of Medicine Ramathibodi Hospital, Mahidol University
 Thailand Ministry of Public Health
 Faculty of Medicine, Thammasat University
 Thammasat University
 Queen Sirikit National Institute of Child Health
 Phramongkutklao College of Medicine
 Faculty of Medicine, Chulalongkorn University

Abstract

Aims/Introduction: The Thai Type 1 Diabetes and Diabetes Diagnosed Before Age 30 Years Registry, Care and Network was established in 2014 and involved 31 hospitals. The objective of the registry was to evaluate glycemic control and complications of patients with type 1 diabetes. Materials and Methods: Patients’ demographics, clinical data, frequencies of daily self-monitoring of blood glucose (SMBG), glycemic control and complications were collected. Results: Among the 1,907 type 1 diabetes patients, the mean age was 21.2 ± 11.3 years. The mean glycated hemoglobin level was 9.35 ± 2.41%, with significant variations among age groups (P < 0.001). Conventional insulin treatment and intensive insulin treatment were used in 43 and 57% of patients, respectively. Mean glycated hemoglobin levels were significantly higher in patients treated with conventional insulin treatment compared to those treated with intensive insulin treatment (9.63 ± 2.34 vs 9.17 ± 2.46%, P = 0.002). Compared to the conventional insulin treatment group, significantly more patients in the intensive insulin treatment group achieved good glycemic control (P < 0.001), and fewer had diabetic retinopathy (P = 0.031). The prevalence of microvascular complications increased significantly with age (P < 0.001). Multivariate analysis showed good glycemic control to be associated with age 25 to <45 years, intensive insulin treatment with SMBG three or more times daily and diabetes duration of 1 to <5 years. Conclusions: Most Thai type 1 diabetes patients were not meeting the recommended glycemic target. As a result of this study, the national program to improve the quality of diabetes treatment and education has been implemented, and the results are ongoing.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/78306

Collections

Scopus 2021