Publication:
Erosive osteoarthritis during treatment with bevacizumab and paclitaxel in a patient with recurrent papillary serous carcinoma of the ovary

Issued Date

2008-03-01

Resource Type

Article

ISSN

15251438
1048891X

DOI

10.1111/j.1525-1438.2007.01023.x

Other identifier(s)

2-s2.0-40549104502

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

International Journal of Gynecological Cancer. Vol.18, No.2 (2008), 379-383

Suggested Citation

A. Jaishuen, J. P. Berrios-Rivera, N. Sirisabya, H. G. Zheng, Y. Li, J. J. Kavanagh Erosive osteoarthritis during treatment with bevacizumab and paclitaxel in a patient with recurrent papillary serous carcinoma of the ovary. International Journal of Gynecological Cancer. Vol.18, No.2 (2008), 379-383. doi:10.1111/j.1525-1438.2007.01023.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19747

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Title

Erosive osteoarthritis during treatment with bevacizumab and paclitaxel in a patient with recurrent papillary serous carcinoma of the ovary

Author(s)

A. Jaishuen
 J. P. Berrios-Rivera
 N. Sirisabya
 H. G. Zheng
 Y. Li
 J. J. Kavanagh

Other Contributor(s)

University of Texas MD Anderson Cancer Center
 Mahidol University

Abstract

Bevacizumab (BVC) is currently used in recurrent ovarian cancer and as part of the initial treatment for ovarian cancer. The most serious toxicities associated with BVC include gastrointestinal perforations, delayed wound healing, and hemorrhage. Arthritis had never been addressed in patients who received BVC treatment. This is the first case report of arthritis emergence linked to BVC administration. A 59-year-old female with recurrent ovarian cancer received multiple hormonal and cytotoxic regimens for 5 years and then developed erosive osteoarthritis of the hands secondary to BVC and paclitaxel. This effect was confirmed by a significant improvement in her symptoms and signs, after treatment was discontinued. © 2007, Copyright the Authors.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/19747

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Scopus 2006-2010