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In vitro studies of the normal human B lymphocyte receptors for preformed solluble dengue antigen-antibody complexes

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dc.contributor.authorS. Boonpucknavigen_US
dc.contributor.authorJ. Siriponten_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-04-30T08:36:43Z
dc.date.available2018-04-30T08:36:43Z
dc.date.issued1980-01-01en_US
dc.description.abstractPreformed soluble dengue antigen-antibody with or without complement complexes could bind to the surface of human lymphocytes via IgG (Fc) or complement receptors respectively. It may be that these lymphocytes were B lymphocytes not T lymphocytes. Dengue antigen or antibody alone will not attach to the surface of those cells. It is emphasized that dengue antigen-antibody complexes can form in the circulation and some will bind to the surface of the B lymphocytes in vivo and play a significant role in the pathogenesis of dengue haemorrhagic fever. In addition mice could develop glomerulonephritis by injection with preformed soluble dengue antigen-antibody complexes. These mice showed proteinuria and deposits of the immune complexes in the glomeruli of the kidneys.en_US
dc.identifier.citationClinical and Experimental Immunology. Vol.39, No.3 (1980), 676-682en_US
dc.identifier.issn00099104en_US
dc.identifier.other2-s2.0-0018876969en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/11108
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0018876969&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleIn vitro studies of the normal human B lymphocyte receptors for preformed solluble dengue antigen-antibody complexesen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0018876969&origin=inwarden_US

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