Publication: Bioactive 4-hydroxycinnamide and bioactivities of polyalthia cerasoides
Issued Date
2011-08-22
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ISSN
16112156
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2-s2.0-80051777986
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Mahidol University
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SCOPUS
Bibliographic Citation
EXCLI Journal. Vol.10, (2011), 16-22
Suggested Citation
Lertyot Treeratanapiboon, Apilak Worachartcheewan, Thummaruk Suksrichavalit, Rachada Kiatfuengfoo, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul Bioactive 4-hydroxycinnamide and bioactivities of polyalthia cerasoides. EXCLI Journal. Vol.10, (2011), 16-22. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/11281
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Title
Bioactive 4-hydroxycinnamide and bioactivities of polyalthia cerasoides
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Abstract
Constituents from Polyalthia cerasoides, stem bark methanol extract, were previously documented. This study reports the first isolation of bioactive N-(4-hydroxy-β-phenethyl)-4- hydroxycinnamide (1) from ethyl acetate extract of the plant species including stigmasterol and a mixture of triterpenes from hexane and dichloromethane extracts. Trace essential elements were found in the hexane extract in ppm level. The plant extracts were evaluated for their antimicrobial and antioxidative activities. The dichloromethane extract displayed the highest activity against Corynebacterium diphtheriae NCTC 10356 with MIC of 32 μg/mL, as well as, the highest SOD activity with an IC 50 of 4.51 μg/mL.