Publication: Quality of life among liver transplantation patients
Issued Date
2012-03-01
Resource Type
ISSN
18732623
00411345
00411345
Other identifier(s)
2-s2.0-84858233989
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Mahidol University
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SCOPUS
Bibliographic Citation
Transplantation Proceedings. Vol.44, No.2 (2012), 532-538
Suggested Citation
Y. Sirivatanauksorn, W. Dumronggittigule, S. Limsrichamrern, C. Iramaneerat, T. Kolladarungkri, P. Kositamongkol, P. Mahawithitwong, S. Asavakarn, C. Tovikkai Quality of life among liver transplantation patients. Transplantation Proceedings. Vol.44, No.2 (2012), 532-538. doi:10.1016/j.transproceed.2011.12.056 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/14920
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Title
Quality of life among liver transplantation patients
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Abstract
Background: Orthotopic liver transplantation (OLT) is the treatment of choice for end-stage disease. It offers a chance to return to an active and prolonged life. Recently, more attention is being paid to the health-related quality of life (HRQoL) of patients and their spouses or caregivers after OLT. The aim of this study was to analyze the pre- versus posttransplantation HRQoL of patients and their spouses or caregivers using generic and disease-specific health questionnaires. Material and Methods: The study was performed between October 2010 and January 2011 using the Short Form-36 (SF-36) and the Chronic Liver Disease Questionnaire (CLDQ) to evaluate the HRQoL. Results: Posttransplantation patients (N = 59, mean age 53.39 [range, 23 to 76] years, male 63.2%, female 36.8%) and their spouses and caregivers showed significantly better generic SF-36 HRQoL scores, namely, physical and social functioning, role limitations because of physical or emotional problems, bodily pain, vitality, as well as general and mental health compared with pretransplantation patients (N = 57, mean age 54.56 (range, 22 to 69) years, male 71.2%, female 28.8%). Similarly, the posttransplantation group showed significantly improved CLDQ scores in all domains: fatigue, activity, abdominal symptoms, systemic symptoms, emotional function, and worry. Conclusion: OLT improved HRQoL of end-stage liver patients and their spouses or caregivers. © 2012 by Elsevier Inc. All rights reserved.