Publication: NK/T-cell lymphoma of the nasal cavity causing contralateral dacryoadenitis
Issued Date
2013-08-01
Resource Type
ISSN
17445108
01676830
01676830
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2-s2.0-84879681698
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Mahidol University
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SCOPUS
Bibliographic Citation
Orbit. Vol.32, No.4 (2013), 250-252
Suggested Citation
Panitee Luemsamran, Kanograt Pornpanich, Mongkol Uiprasertkul, Natta Sakolsatayadorn, Sumalee Vangveeravong NK/T-cell lymphoma of the nasal cavity causing contralateral dacryoadenitis. Orbit. Vol.32, No.4 (2013), 250-252. doi:10.3109/01676830.2013.788665 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/32223
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Title
NK/T-cell lymphoma of the nasal cavity causing contralateral dacryoadenitis
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Abstract
Purpose: To report a case of NK/T-cell lymphoma of the nasal cavity with contralateral lacrimal gland involvement. Methods: Observational case report. Results: A 39-year-old woman with a 5-month history of right fungal rhinosinusitis was referred to our hospital. A nasal mucosal biopsy performed before referral was consistent with Aspergillus sp. Despite surgical and parenteral antifungal treatment, the symptoms continued to deteriorate. On admission, the ophthalmic evaluation showed inflammation over the left lacrimal gland area. The fundus examination revealed bilateral subretinal infiltration. Computed tomography scans of the orbits and sinuses showed mucosal thickening of the right nasal mucosa and sinuses. There was heterogeneous enhancement and infiltration of the left lacrimal gland. Lacrimal gland biopsy and repeated biopsies of the nasal cavity and sinus tissue were performed. Immunohistopathology of the lacrimal glands and nasal mucosa showed extranodal nasal-type NK/T-cell lymphoma. The patient was treated with cyclophosphamide, vincristine, adriamycin, prednisolone (3 cycles), and intrathecal methotrexate. The patient developed sepsis and died 2 months after initiation of chemotherapy. Conclusion: Dacryoadenitis can be a clinical manifestation of NK/T-cell lymphoma. To our knowledge, this is the first reported case of nasal NK/T-cell lymphoma with contralateral dacryoadenitis. © 2013 Informa Healthcare USA, Inc. All rights reserved: reproduction in whole or part not permitted.