Publication: Paclitaxel-eluting balloon angioplasty and cobalt-chromium stents versus conventional angioplasty and paclitaxel-eluting stents in the treatment of native coronary artery stenoses in patients with diabetes mellitus
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Issued Date
2011-05-01
Resource Type
ISSN
19696213
1774024X
1774024X
Other identifier(s)
2-s2.0-80155154054
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Mahidol University
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SCOPUS
Bibliographic Citation
EuroIntervention. Vol.7, No.SUPPL. K (2011)
Suggested Citation
Rosli Mohd Ali, Ralf Degenhardt, Robaayah Zambahari, Damras Tresukosol, Wan Azman Wan Ahmad, Haizal Bin Haron Kamar, Sim Kui-Hian, Tiong Kiam Ong, Omar Bin Ismail, Safari Bin Elis, Wasan Udychalerm, Hanns Ackermann, Michael Boxberger, Martin Unverdorben Paclitaxel-eluting balloon angioplasty and cobalt-chromium stents versus conventional angioplasty and paclitaxel-eluting stents in the treatment of native coronary artery stenoses in patients with diabetes mellitus. EuroIntervention. Vol.7, No.SUPPL. K (2011). doi:10.4244/EIJV7SKA15 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/12532
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Title
Paclitaxel-eluting balloon angioplasty and cobalt-chromium stents versus conventional angioplasty and paclitaxel-eluting stents in the treatment of native coronary artery stenoses in patients with diabetes mellitus
Other Contributor(s)
Institut Jantung Negara Kuala Lumpur
Center for Cardiovascular Diseases
Mahidol University
University of Malaya Medical Centre
Sarawak Hospital
Penang Hospital
King Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn University
Goethe-Universitat Frankfurt am Main
Vascular System
B. Braun Medical Inc.
Center for Cardiovascular Diseases
Mahidol University
University of Malaya Medical Centre
Sarawak Hospital
Penang Hospital
King Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn University
Goethe-Universitat Frankfurt am Main
Vascular System
B. Braun Medical Inc.
Abstract
Aims: Coronary lesions in diabetics (DM) are associated with a high recurrence following percutaneous coronary intervention (PCI), even after drug-eluting stent (DES) deployment. Encouraging clinical data of the drug-eluting balloon catheter (DEB) SeQuent Please warrant its investigation in these patients. Methods and results: Eighty-four diabetic patients (60.8±9.1years, 76.2% male) were randomised to either the DEB SeQuent™ Please or the DES Taxus™ Liberte™ to compare the 9-month clinical and angiographic outcome of PCI in native coronary arteries. Comparing the DEB vs. the DES the 9-month results (follow-up DEB 39/45 [86.7%], DES 36/39 [92.3%] ) are statistically not different at the 0.05 level for the primary end- point of in-segment (0.37±0.59 mm vs. 0.35 ±0.63 mm) and in-stent (0.51±0.61 mm vs. 0.53±0.67 mm) late lumen loss, overall and cardiac deaths (2/45 [4.4%] and 3/45 [6.7%] vs. 0), target lesion revascularisation (3/45 [8.9%] vs. 4/39 [10.3%] ), the total MACE rate (6/45 [13.3%] vs. 6/39 [15.4%] ), and the event free survival after 10.2±3.8 months (Kaplan-Meier analysis, p < 0.80, log rank test). Conclusions: The clinical and angiographic outcome of the combination of the drug-eluting balloon SeQuent Please with a cobalt chromium stent compared to the drug eluting Taxus stent are similar. © Europa Edition 2011. All rights reserved.