Publication: The quest of vision: retina’s daily challenges
Issued Date
2020-01-01
Resource Type
ISSN
17401194
0954982X
0954982X
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2-s2.0-85096878264
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Mahidol University
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SCOPUS
Bibliographic Citation
Biochemist. Vol.42, No.5 (2020), 4-10
Suggested Citation
Dhanach Dhirachaikulpanich, Robert A.I. Paraoan, Emil Carlsson, Luminita Paraoan The quest of vision: retina’s daily challenges. Biochemist. Vol.42, No.5 (2020), 4-10. doi:10.1042/bio20200061 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/60407
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Title
The quest of vision: retina’s daily challenges
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Abstract
© 2020 The Authors. Published by Portland Press Limited under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) The retina is a complex biological structure located at the back of the eye. Every day, it continually performs an intricate set of tasks to provide us with the sense of vision. The neuroretina encompasses neuronal type of cells including the light-sensitive photoreceptors, which sense the incoming light and trigger the conversion of the visual stimulus information to a neural response relayed to our brain where images are created. This article focuses on the physiological processes occurring in the retina and the exquisite interplay between photoreceptors and the adjacent cell monolayer called the retinal pigment epithelium, which underpins the key visual processes of phototransduction, visual cycle and phagocytosis of spent photoreceptors’ outer segments. We also present examples of functional defects in the retina and how they lead to impaired vision or blindness, and discuss some emerging treatment options for retinal diseases.