Publication: Intestinal microsporidiosis in hiv-infected children with diarrhea
Issued Date
2002-12-01
Resource Type
ISSN
01251562
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2-s2.0-0036597856
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.33, No.2 (2002), 241-245
Suggested Citation
Darawan Wanachiwanawin, Kulkanya Chokephaibulkit, Punpob Lertlaituan, Jeerawan Ongrotchanakun, Pisith Chinabut, Kleophant Thakerngpol Intestinal microsporidiosis in hiv-infected children with diarrhea. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.33, No.2 (2002), 241-245. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20279
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Title
Intestinal microsporidiosis in hiv-infected children with diarrhea
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Abstract
Intestinal microsporidiosis is a common opportunistic disease associated with diarrhea in adult AIDS patients in Thailand; the data regarding this infection in children are scarce. The present study was designed to investigate the prevalence and clinical features of intestinal microsporidiosis in hospitalized HIV-infected and uninfected (free of HIV) children with diarrhea. Of the 95 HIV-infected children and 87 uninfected children, 24 (25.3%) and 13 (14.9%) respectively were diagnosed with intestinal microsporidiosis. Species identification of microsporidia spores, by transmission electron microscopy, demonstrated Enterocytozoon bieneusi in 5 cases. Cryptosporidium parvum was a common coinfective parasite; pneumonia was the most frequent concurrent disease found in children with intestinal microsporidiosis. Malnutrition was commoner in the HIV-infected group (79.2% vs 23.1%; p = 0.003). This study indicates that intestinal microsporidiosis is an important disease in both HIV-infected and uninfected Thai children with diarrhea.