Publication: Pituitary hyperplasia mimicking thyrotropin-producing pituitary adenoma in the patient with resistance to thyroid hormone: a case report
Issued Date
2020-01-01
Resource Type
ISSN
15635279
00207454
00207454
Other identifier(s)
2-s2.0-85089017884
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Neuroscience. (2020)
Suggested Citation
Onnicha Suntornlohanakul, Chutintorn Sriphrapradang Pituitary hyperplasia mimicking thyrotropin-producing pituitary adenoma in the patient with resistance to thyroid hormone: a case report. International Journal of Neuroscience. (2020). doi:10.1080/00207454.2020.1803304 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/58348
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Title
Pituitary hyperplasia mimicking thyrotropin-producing pituitary adenoma in the patient with resistance to thyroid hormone: a case report
Abstract
© 2020 Informa UK Limited, trading as Taylor & Francis Group. The syndrome of inappropriate thyroid-stimulating hormone (TSH) secretion is characterized by high circulating thyroid hormone concentrations in the presence of non-suppressed TSH. After exclusion of the laboratory interference, TSH-secreting pituitary adenoma (TSHoma) or resistance to thyroid hormone-beta (RTH-β) should be suspected. The presence of a pituitary adenoma on the hypothalamic-pituitary imaging supports the diagnosis of TSHoma. However, the incidental findings of non-functioning pituitary adenomas may appear in patients with RTH-β. Abnormal MRI finding in the RTH-β patient also includes pituitary enlargement from thyrotroph hyperplasia. We herein reported a patient with inappropriate TSH secretion who has pituitary hyperplasia mimicking TSHoma. This case illustrates the diagnostic tests to distinguish an RTH-β from TSHoma.