Publication:
Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida

3

Issued Date

2016-01-01

Resource Type

Article

ISSN

20402511
20402503

DOI

10.1039/c6md00365f

Other identifier(s)

2-s2.0-84991404778

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

MedChemComm. Vol.7, No.10 (2016), 1952-1956

Suggested Citation

Matthew D. Stephens, Nisakorn Yodsanit, Christian Melander Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida. MedChemComm. Vol.7, No.10 (2016), 1952-1956. doi:10.1039/c6md00365f Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/43169

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Title

Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida

Author(s)

Matthew D. Stephens
 Nisakorn Yodsanit
 Christian Melander

Other Contributor(s)

North Carolina State University
 Mahidol University

Abstract

© 2016 The Royal Society of Chemistry. A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the Francisella sub-species F. novicida and F. philomiragia.

Keyword(s)

Biochemistry, Genetics and Molecular Biology

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/43169

Collections

Scopus 2016-2017