Publication: Multisystem inflammatory syndrome associated with sars-cov-2 infection in an adult: A case report from the maldives
Issued Date
2021-12-01
Resource Type
ISSN
24146366
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2-s2.0-85118159146
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Mahidol University
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SCOPUS
Bibliographic Citation
Tropical Medicine and Infectious Disease. Vol.6, No.4 (2021)
Suggested Citation
Ahmed Miqdhaadh, Hisham Ahmed Imad, Aminath Fazeena, Thundon Ngamprasertchai, Wang Nguitragool, Emi E. Nakayama, Tatsuo Shioda Multisystem inflammatory syndrome associated with sars-cov-2 infection in an adult: A case report from the maldives. Tropical Medicine and Infectious Disease. Vol.6, No.4 (2021). doi:10.3390/tropicalmed6040187 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/77142
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Title
Multisystem inflammatory syndrome associated with sars-cov-2 infection in an adult: A case report from the maldives
Abstract
The multisystem inflammatory syndrome in adults (MIS-A) is a novel syndrome observed during COVID-19 outbreaks. This hyper-inflammatory syndrome is seen predominantly in children and adolescents. The case of an adult from the Maldives who had asymptomatic SARS-CoV-2 infection three weeks before presenting to the hospital with fever, rash, and shock is presented. De-identified clinical data were retrospectively collected to summarize the clinical progression and treatment during hospitalization and the six-month follow-up. SARS-CoV-2 infection was confirmed by RT-PCR. Other laboratory findings included anemia (hemoglobin: 9.8 g/dL), leukocytosis (leuko-cytes: 20,900/µL), neutrophilia (neutrophils: 18,580/µL) and lymphopenia (lymphocytes: 5067/µL), and elevated inflammatory markers, including C-reactive protein (34.8 mg/dL) and ferritin (2716.0 ng/dL). The electrocardiogram had low-voltage complexes, and the echocardiogram showed hypokinesia, ventricular dysfunction, and a pericardial effusion suggestive of myocardial dysfunction compromis-ing hemodynamics and causing circulatory shock. These findings fulfilled the diagnostic criteria of MIS-A. The case was managed in the intensive care unit and required non-invasive positive pressure ventilation, inotropes, and steroids. With the new surges of COVID-19 cases, more cases of MIS-A that require the management of organ failure and long-term follow-up to recovery are anticipated. Clinicians should therefore be vigilant in identifying cases of MIS-A during the pandemic.