Publication: Diterpenes, sesquiterpenes, and a sesquiterpene-coumarin conjugate from Jatropha integerrima
Issued Date
2009-11-30
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ISSN
01633864
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2-s2.0-73349140850
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Natural Products. Vol.72, No.11 (2009), 2024-2027
Suggested Citation
Somyote Sutthivaiyakit, Wantana Mongkolvisut, Samran Prabpai, Palangpon Kongsaeree Diterpenes, sesquiterpenes, and a sesquiterpene-coumarin conjugate from Jatropha integerrima. Journal of Natural Products. Vol.72, No.11 (2009), 2024-2027. doi:10.1021/np900342b Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/27113
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Title
Diterpenes, sesquiterpenes, and a sesquiterpene-coumarin conjugate from Jatropha integerrima
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Abstract
Five new compounds, 2α-hydroxyjatropholone (1), 2β- hydroxyjatropholone (2), 1,5-dioxo-2,3-dihydroxyrhamnofola-4(10),6,11(18),15- tetraene (3), 2-keto-5-hydroxyguai-3,11-diene (4), and a sesquiterpene - coumarin conjugate, jatrophadioxan (5), and nine known compounds have been isolated from the roots of Jatropha integerrima. The structures were established from spectroscopic data, and the relative configuration of 1 was confirmed by X-ray crystallography. Six diterpenes were evaluated for their antiplasmodial, antituberculosis, and cytotoxic activities. © 2009 American Chemical Society and American Society of Pharmacognosy.