Publication: Lethal Malaria: Marchiafava and Bignami Were Right
Issued Date
2013-07-15
Resource Type
ISSN
00221899
Other identifier(s)
2-s2.0-84879331864
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Infectious Diseases. Vol.208, No.2 (2013), 192-198
Suggested Citation
Nicholas J. White, Gareth D.H. Turner, Nicholas P.J. Day, Arjen M. Dondorp Lethal Malaria: Marchiafava and Bignami Were Right. Journal of Infectious Diseases. Vol.208, No.2 (2013), 192-198. doi:10.1093/infdis/jit116 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/32259
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Lethal Malaria: Marchiafava and Bignami Were Right
Other Contributor(s)
Abstract
One hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed that the fundamental pathological process underlying lethal falciparum malaria was microvascular obstruction. Since then, several alternative hypotheses have been proposed. These formed the basis for adjunctive interventions, which have either been ineffective or harmful. Recent evidence strongly suggests that Marchiafava and Bignami were right. © 2013 The Author 2013. Published by Oxford University Press on behalf of the Infectious Disease Society of America.