Publication:
International collaborative survey on epidemiology of hepatitis E virus in 11 countries

Issued Date

2006-01-01

Resource Type

Review

ISSN

01251562

Other identifier(s)

2-s2.0-33744467382

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.1 (2006), 90-95

Suggested Citation

Kenji Abe, Tian Cheng Li, Xin Ding, Khin Maung Win, Pradeep Krishna Shrestha, Vo Xuan Quang, Trinh Thi Ngoc, Teresa Casanovas Taltavull, Andrei V. Smirnov, Vasily F. Uchaikin, Pairoj Luengrojanakul, Hongxi Gu, Abdel Rahman El-Zayadi, Alfred M. Prince, Kaoru Kikuchi, Naohiko Masaki, Ayano Inui, Tetsutaro Sata, Naokazu Takeda International collaborative survey on epidemiology of hepatitis E virus in 11 countries. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.1 (2006), 90-95. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/23877

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Title

International collaborative survey on epidemiology of hepatitis E virus in 11 countries

Author(s)

Kenji Abe
 Tian Cheng Li
 Xin Ding
 Khin Maung Win
 Pradeep Krishna Shrestha
 Vo Xuan Quang
 Trinh Thi Ngoc
 Teresa Casanovas Taltavull
 Andrei V. Smirnov
 Vasily F. Uchaikin
 Pairoj Luengrojanakul
 Hongxi Gu
 Abdel Rahman El-Zayadi
 Alfred M. Prince
 Kaoru Kikuchi
 Naohiko Masaki
 Ayano Inui
 Tetsutaro Sata
 Naokazu Takeda

Other Contributor(s)

National Institute of Infectious Diseases
 Yangon General Hospital
 Tribhuvan University Teaching Hospital
 Cho Ray Hospital
 Bach Mai Hospital
 Hospital Universitari de Bellvitge
 Pirogov Russian National Research Medical University (RNRMU)
 Mahidol University
 Harbin Medical University
 Cairo Liver Center
 New York Blood Center
 Okinawa Chubu Hospital
 National Center for Global Health and Medicine
 International University of Health and Welfare

Abstract

We conducted seroepidemiological studies on antibody prevalence to hepatitis E virus (HEV) in 5,233 sera from 11 countries to ascertain the present state of HEV infection on a global basis. The prevalence of anti-HEV IgG increased with age in these tested countries, but the rate of antibody positivity was over 20% in the 16-30 year-old group in most of the participating countries, except for Japan, the USA, and Spain. Of patients with acute hepatitis of unknown etiology from Nepal, 56% (14/25) were positive for the IgM class of anti-HEV antibody. In addition, HEV RNAs in the serum from 3 Nepali patients who had the IgM antibody were detected by nested PCR and all of the HEV genes isolated belonged to genotype 1. Our results indicate that HEV is spreading worldwide, not only in developing countries, but also in more industrialized countries than previously thought.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/23877

Collections

Scopus 2006-2010