Publication: Diterpenoids from the roots of Croton oblongifolius
Issued Date
2007-11-01
Resource Type
ISSN
00320943
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2-s2.0-36949003723
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Mahidol University
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SCOPUS
Bibliographic Citation
Planta Medica. Vol.73, No.14 (2007), 1491-1494
Suggested Citation
Witoon Youngsa-ad, Nattaya Ngamrojanavanich, Chulabhorn Mahidol, Somsak Ruchirawat, Hunsa Prawat, Prasat Kittakoop Diterpenoids from the roots of Croton oblongifolius. Planta Medica. Vol.73, No.14 (2007), 1491-1494. doi:10.1055/s-2007-990247 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/23969
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Title
Diterpenoids from the roots of Croton oblongifolius
Abstract
Two new clerodane diterpenes, methyl 15,16-epoxy-3,13(16),14-ent- clerodatrien-18,19-olide-17-carboxylate (1) and dimethyl 15,16-epoxy-12-oxo-3, 13(16),14-ent-clerodatriene-17,18-dicarboxylate (2), together with seven known compounds (3-9), were isolated from the roots of Croton oblongifolius. The isolated compounds showed only mild cytotoxic activity against HuCCA-1, KB, HeLa, MDA-MB231, and T47D cell lines with IC50 values ranging from 10 to 50 μg/mL. © Georg Thieme Verlag KG Stuttgart.