Publication:
Electron microscopic study of glomerular filtration barrier in the rat kidney embedded in polymerized glutaraldehyde-urea

Issued Date

1979-01-01

Resource Type

Article

ISSN

14226421
14226405

DOI

10.1159/000145156

Other identifier(s)

2-s2.0-84940141200

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Cells Tissues Organs. Vol.105, No.4 (1979), 494-504

Suggested Citation

Prasert Sobhon Electron microscopic study of glomerular filtration barrier in the rat kidney embedded in polymerized glutaraldehyde-urea. Cells Tissues Organs. Vol.105, No.4 (1979), 494-504. doi:10.1159/000145156 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/13254

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Electron microscopic study of glomerular filtration barrier in the rat kidney embedded in polymerized glutaraldehyde-urea

Author(s)

Prasert Sobhon

Other Contributor(s)

Mahidol University

Abstract

Embedding kidney in polymerized glutaraldehyde-urea favors the retention of glycoprotein matrix of the cell coat and the basement membrane of the glomeruli. The basement membrane appears as a single layer with uniform amorphous matrix. Thick glycoprotein coat covers the whole surface of prodocytes and their foot processes. In areas other than the slits and the portion of the foot processes which touch on the basement membrane, the coat is a continuous layer with an average thickness of 490 Å. In the slits between the foot processes of podocytes there is an actual fusion of glycoprotein coats; the average width of the slit is 415 Å. The glycoprotein ‘plugs’ in the slit may be a significant portion of the glomerular filtration barrier against macromolecules, together with the basement membrane and the slit diaphragms. © 1979 S. Karger AG, Basel.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/13254

Collections

Scopus 1969-1990