Publication: Glutarimide alkaloids and a terpenoid benzoquinone from Cordia globifera
| dc.contributor.author | Joshua Parks | en_US |
| dc.contributor.author | Thinley Gyeltshen | en_US |
| dc.contributor.author | Vilailak Prachyawarakorn | en_US |
| dc.contributor.author | Chulabhorn Mahidol | en_US |
| dc.contributor.author | Somsak Ruchirawat | en_US |
| dc.contributor.author | Prasat Kittakoop | en_US |
| dc.contributor.other | Chulabhorn Research Institute | en_US |
| dc.contributor.other | University of Portland | en_US |
| dc.contributor.other | Chulabhorn Graduate Institute | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-09-24T08:45:04Z | |
| dc.date.available | 2018-09-24T08:45:04Z | |
| dc.date.issued | 2010-05-28 | en_US |
| dc.description.abstract | Three new compounds, a meroterpene (2) having a cyclopropane moiety named globiferane and glutarimide alkaloids named cordiarimides A (3) and B (4), were isolated from the roots of Cordia globifera. Compounds 2-4 exhibited weak cytotoxic activity. Cordiarimide B (4) exhibited radical scavenging activity, as it inhibited superoxide anion radical formation in the xanthine/xanthine oxidase (XXO) assay, and also suppressed superoxide anion generation in differentiated HL-60 human promyelocytic leukemia cells when induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). This is the first report on the presence of glutarimide alkaloids in the genus Cordia. © 2010 The American Chemical Society and American Society of Pharmacognosy. | en_US |
| dc.identifier.citation | Journal of Natural Products. Vol.73, No.5 (2010), 992-994 | en_US |
| dc.identifier.doi | 10.1021/np100078s | en_US |
| dc.identifier.issn | 15206025 | en_US |
| dc.identifier.issn | 01633864 | en_US |
| dc.identifier.other | 2-s2.0-77952974771 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/28706 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952974771&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Glutarimide alkaloids and a terpenoid benzoquinone from Cordia globifera | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952974771&origin=inward | en_US |
