Publication: Evaluation of retinal structure in unilateral amblyopia using spectral domain optical coherence tomography
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Issued Date
2018-10-01
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15283933
10918531
10918531
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2-s2.0-85054036906
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of AAPOS. Vol.22, No.5 (2018), 386-389
Suggested Citation
Apatsa Lekskul, Wadakarn Wuthisiri, Tanyatuth Padungkiatsagul Evaluation of retinal structure in unilateral amblyopia using spectral domain optical coherence tomography. Journal of AAPOS. Vol.22, No.5 (2018), 386-389. doi:10.1016/j.jaapos.2018.05.014 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/46268
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Title
Evaluation of retinal structure in unilateral amblyopia using spectral domain optical coherence tomography
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Abstract
© 2018 American Association for Pediatric Ophthalmology and Strabismus Purpose: To investigate potential differences in the retinal nerve fiber layer (RNFL) thickness, macular thickness and foveal thickness between amblyopic eyes and normal fellow eyes on spectral domain optical coherence tomography (SD-OCT). Methods: A cross-sectional study of patients ≥10 years of age with unilateral amblyopia resulting from an anisometropic, strabismic or deprivative cause. Comprehensive ophthalmic examination was completed and the retinal structures of both eyes were measured using SD-OCT. We compared the measurements obtained between the amblyopic eye and the fellow normal eye in each subject. Results: Twenty-six unilateral amblyopia patients with a mean age of 29.92 ± 14.19 years old participated in the study, of which 17 (65.4%) were classified as anisometropic, 7 (26.9%) as strabismic, and 2 (7.7%) as deprivative. For the amblyopic eye and fellow normal eye, respectively, the mean RNFL thickness was 95.87 ± 14.56 μm and 97.87 ± 14.56 μm (P = 0.628), the mean macular thickness was 270.87 ± 14.43 μm and 275.60 ± 14.43 μm (P = 0.251) and the mean foveal thickness was 250.59 ± 27.82 μm and 242.91 ± 27.82 μm (P = 0.332). SD-OCT assessments revealed no statistically significant differences between both eyes. Conclusions: Using SD-OCT, there were no significant changes in the retinal structure of amblyopic eyes. Therefore, amblyopia does not seem to have a profound structural effect on the retinal nerve fiber layer, the macula, or the fovea.