Transport of Folate cofactors by Plasmodium Falciparum infected Red blood cells
2
Issued Date
1989
Copyright Date
1989
Resource Type
Language
eng
File Type
application/pdf
No. of Pages/File Size
vii, 118 leaves : ill.
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thesis (M.Sc. (Biochemistry))--Mahidol University, 1989
Suggested Citation
Sataporn Suttikulpitug Transport of Folate cofactors by Plasmodium Falciparum infected Red blood cells. Thesis (M.Sc. (Biochemistry))--Mahidol University, 1989. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/103560
Title
Transport of Folate cofactors by Plasmodium Falciparum infected Red blood cells
Alternative Title(s)
การขนส่งโฟเลตเข้าสู่เม็ดเลือดแดงที่ติดเชื้อพลาสโมเดียมฟัลซิพารั่ม
Author(s)
Abstract
Study of folate uptake by P.falciparum infected red blood cells indicated that the increase in rated of uptake resulted form the intracellular parasites. Folate uptake was highest at the schizont stage and was icreased with percent parasitemia. The uptake was neither a carrier-mediated nor an active transport because it could not be competitively inhibited by folate analogues, was not dependent on cellular energy, and showed no saturation with folate concentration in the transporting medium. The data primarily suggested that the uptake was through pores formed during infection by the malarial parasite. From the present study the existence of a possible folate salvage pathway in P.falciparum could not be demonstrated.
Description
Biochemistry (Mahidol University 1989)
Degree Name
Master of Science
Degree Level
Master's degree
Degree Department
Faculty of Science
Degree Discipline
Biochemistry
Degree Grantor(s)
Mahidol University