Cancer in pregnancy: FIGO Best practice advice and narrative review
Issued Date
2025-01-01
Resource Type
ISSN
00207292
eISSN
18793479
Scopus ID
2-s2.0-105013759165
Pubmed ID
40704672
Journal Title
International Journal of Gynecology and Obstetrics
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Gynecology and Obstetrics (2025)
Suggested Citation
Nanda S., Nana M., Nguyen-Hoang L., Adam S., McAuliffe F., Bergman L., Wilailak S., McNally O., Maxwell C.V., Purandare N., Jacobsson B., Medina V.P., Kapur A., Beyuo T., Ruiloba F., Castelazo E., Smith G.N., O'Reilly S.L., O'Brien P., Hanson M., Rosser M.L., Sosa C., Guinto V., Berek J., Nelson-Piercy C., Amant F., Poon L. Cancer in pregnancy: FIGO Best practice advice and narrative review. International Journal of Gynecology and Obstetrics (2025). doi:10.1002/ijgo.70258 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/111854
Title
Cancer in pregnancy: FIGO Best practice advice and narrative review
Author(s)
Author's Affiliation
University College London
KU Leuven
Uppsala Universitet
University of Southampton
Chinese University of Hong Kong
Queen’s University
University College Dublin
Columbia University Irving Medical Center
Stellenbosch University
KU Leuven– University Hospital Leuven
Faculty of Life Sciences & Medicine
Sahlgrenska Universitetssjukhuset
University of Galway
Sahlgrenska Akademin
Stanford Healthcare
King's College Hospital
University of Ghana
Folkehelseinstituttet
University Hospital Southampton NHS Foundation Trust
Universidad del Valle, Cali
Women's College Hospital
University of the Philippines Manila
Royal Women's Hospital, Carlton
Faculty of Medicine Ramathibodi Hospital, Mahidol University
UCD School of Medicine
Evelina London Children's Healthcare
Universidad de la Republica Facultad de Medicina
Faculty of Health Sciences
International Federation of Gynecology and Obstetrics
World Diabetes Foundation
Tam Anh General Hospital
KU Leuven
Uppsala Universitet
University of Southampton
Chinese University of Hong Kong
Queen’s University
University College Dublin
Columbia University Irving Medical Center
Stellenbosch University
KU Leuven– University Hospital Leuven
Faculty of Life Sciences & Medicine
Sahlgrenska Universitetssjukhuset
University of Galway
Sahlgrenska Akademin
Stanford Healthcare
King's College Hospital
University of Ghana
Folkehelseinstituttet
University Hospital Southampton NHS Foundation Trust
Universidad del Valle, Cali
Women's College Hospital
University of the Philippines Manila
Royal Women's Hospital, Carlton
Faculty of Medicine Ramathibodi Hospital, Mahidol University
UCD School of Medicine
Evelina London Children's Healthcare
Universidad de la Republica Facultad de Medicina
Faculty of Health Sciences
International Federation of Gynecology and Obstetrics
World Diabetes Foundation
Tam Anh General Hospital
Corresponding Author(s)
Other Contributor(s)
Abstract
Cancer during pregnancy is relatively rare. The incidence is underestimated due to the lack of international registries covering both high-income and low- and middle-income countries, and is expected to rise with increasing maternal age and increasing global adoption of cell-free DNA testing for aneuploidy. Physiological changes during pregnancy often make the diagnosis challenging and delayed. Lack of experience and knowledge about this condition may also contribute to late diagnosis, suboptimal management, and occasionally inadvertent fetal and/or maternal harm. The principles of cancer management in pregnancy for most cancer types do not differ significantly from the non-pregnant population. The impact of investigations for diagnosis and staging, risks of surgery, systemic chemotherapy, and/or radiotherapy on fetal well-being and preterm birth need to be considered for treatment and management planning, in addition to maternal wishes. Working in a multidisciplinary setting, ideally with medical and radiation oncologists, surgeons, radiologists, cancer specialist nurses, geneticists, psychologists, teratologists, and clinical pharmacologists, obstetricians, obstetric physicians, neonatologists, and experienced nursing and midwifery staff helps provide optimal care for the woman. This best practice advice aims to provide recommendations on the diagnosis and management of cancer in pregnancy, which can be adopted in all resource settings.