273rd ENMC International workshop: Clinico-Sero-morphological classification of the Antisynthetase syndrome. Amsterdam, The Netherlands, 27-29 October 2023
Issued Date
2024-12-01
Resource Type
ISSN
09608966
eISSN
18732364
Scopus ID
2-s2.0-85207665104
Journal Title
Neuromuscular Disorders
Volume
45
Rights Holder(s)
SCOPUS
Bibliographic Citation
Neuromuscular Disorders Vol.45 (2024)
Suggested Citation
Stenzel W., Mammen A.L., Gallay L., Holzer M.T., Kleefeld F., Benveniste O., Allenbach Y., Damoiseaux J., Danoff S.K., Diederichsen L., Fiorentino D., Giannini M., Kolsters L., Lundberg I., Mammen A.L., Meyer A., Minopulou I., Preusse C., Ruck T., Tanboon J., Tansley S.L., Uzunhan Y. 273rd ENMC International workshop: Clinico-Sero-morphological classification of the Antisynthetase syndrome. Amsterdam, The Netherlands, 27-29 October 2023. Neuromuscular Disorders Vol.45 (2024). doi:10.1016/j.nmd.2024.104453 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/101883
Title
273rd ENMC International workshop: Clinico-Sero-morphological classification of the Antisynthetase syndrome. Amsterdam, The Netherlands, 27-29 October 2023
Author's Affiliation
University of Bath, Department of Life Sciences
Siriraj Hospital
Universitätsklinikum Düsseldorf
Stanford University School of Medicine
Charité – Universitätsmedizin Berlin
Hopital Edouard Herriot
Hôpital Universitaire Pitié Salpêtrière
Copenhagen University Hospital
Karolinska Institutet
Les Hôpitaux Universitaires de Strasbourg
University Sorbonne Paris Nord
Maastricht Universitair Medisch Centrum+
National Institutes of Health (NIH)
Universitätsklinikum Hamburg-Eppendorf
Johns Hopkins University School of Medicine
Patient representative
Siriraj Hospital
Universitätsklinikum Düsseldorf
Stanford University School of Medicine
Charité – Universitätsmedizin Berlin
Hopital Edouard Herriot
Hôpital Universitaire Pitié Salpêtrière
Copenhagen University Hospital
Karolinska Institutet
Les Hôpitaux Universitaires de Strasbourg
University Sorbonne Paris Nord
Maastricht Universitair Medisch Centrum+
National Institutes of Health (NIH)
Universitätsklinikum Hamburg-Eppendorf
Johns Hopkins University School of Medicine
Patient representative
Corresponding Author(s)
Other Contributor(s)
Abstract
Among the idiopathic inflammatory myopathies, patients harbouring an Antisynthetase syndrome exhibit a unique clinical picture, with characteristic signs such as myositis, interstitial lung disease, arthritis, rash, and/or fever. Characteristic morphological features on skeletal muscle biopsies differentiate Antisynthetase syndrome from other forms of myositis. Autoantibodies typically recognizing one of the members of the aminoacyl-tRNA synthetase family of proteins can be detected in the serum of such patients, with anti-Jo1 being most frequent. Until now, an international consensus definition of the Antisynthetase syndrome is lacking, hence this workshop has undertaken the task to inform about the clinical, morphological and autoantibody profiles of Antisynthetase syndrome. The authors also expand their aims by giving management and therapeutic strategies, and finally provide precise classification criteria for Antisynthetase syndrome.