Scopus 2024

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    Optic Neuritis
    (2024-01-01) Padungkiatsagul T.; Padungkiatsagul T.; Mahidol University
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    Factors Associated with Violence of Persons with Disabilities in the Thai Context
    (2024-01-01) Auemaneekul N.; Seesaet S.; Lagampan S.; Sujirarat D.; Auemaneekul N.; Mahidol University
    This study used an analytical descriptive research approach, focusing on violence against people with disabilities, the types of violence experiences, and the factors related to the violence among people with disabilities in the Thai context. This study applied the Ecological model for understanding interpersonal violence from the World Health Organization as the theoretical guideline. The calculated samples consisted of 201 people who have a disability aged 20 years old and over. Descriptive statistics were used to describe the general characteristics, and logistic regression was applied for the data analysis. The results revealed that people with disability experienced overall violence at 98%, psychological violence 96.5%, physical violence 77.1%, violence from being neglected 75.6%. Factors influencing violence against people with disabilities composed of younger age, being female, low income, living with illness, poor relationships within the family, less family members, and social values to violence. The result of this study could be beneficial in developing awareness and prevention programs to protect human rights violations against people with disabilities in the Thai context.
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    Established and Emerging Risk Factors of Stroke in Asian Countries: A Systematic Review
    (2024-05-01) Jarintanan P.; Singh N.; Suthienkul O.; Boonkrong P.; Jarintanan P.; Mahidol University
    This paper aims to review the stroke situation regarding its risk factors in 16 Asian countries. From the stroke incidence in 2016 and 2019, it was found that the number of stroke cases per 100,000 people increased in 10 and decreased in 6 Asian countries. Low-middle income countries (LMICs) tend to have lower service and quality of healthcare compared to high-income countries (HICs), this significant difference in healthcare might be what causes the difference in stroke incidence. A systematic review was conducted for identifying and rating the frequency of stroke risk factors. Reviewing 15 selected papers, there are eight risk factors for stroke ranging from hypertension15, diabetes12, hypercholesterolemia/dyslipidemia12, smoking11, physical inactivity7, obesity7, air quality2 to family history1. Age remains a significant risk factor for stroke, underscoring the importance of targeted preventive measures and healthcare interventions for older populations. China, as an example, has spread awareness and shown commitment to health issues and factors, adding institutions, and establishing a healthcare service for locations with more than 300,000. Studies have shown that women in LMICs are more likely to have a stroke at a young age compared to those in HICs, and could be influenced by cultural and social factors on women’s health. Therefore, individuals could decrease stroke risk through healthy lifestyle choices, preventing hypertension, diabetes, and hypercholesterolemia/dyslipidemia. Lifestyle modifications including not smoking, maintaining a healthy diet, and exercising regularly should lower the risk of stroke occurrence in individuals. Simultaneously, national policies could lower stroke incidences by strengthening the stroke care ecosystem.
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    Cytotaxonomy of Kaempferia subg. Protanthium (Zingiberaceae) supports a new limestone species endemic to Thailand
    (2024-06-28) Nopporncharoenkul N.; Sukseansri W.; Nopun P.; Meewasana J.; Jenjittikul T.; Chuenboonngarm N.; Viboonjun U.; Umpunjun P.; Nopporncharoenkul N.; Mahidol University
    Thailand is the biodiversity hotspot of genus Kaempferia (Zingiberaceae) and harbours 14 species belonging to K. subgenus Protanthium. To better understand the taxonomic circumscription and verify the taxonomic status, the present characterization of cytogenetic characters included all recognized and one undescribed species of K. subg. Protanthium from Thailand. Overall, 88 accessions of plant materials were analysed cytogenetically: 84 and 42 accessions were subjected to flow cytometry and karyology, respectively. Based on genome size and mitotic chromosome numbers, 74 accessions from all species investigated were putative diploid, whereas the others were putative polyploid: triploid (three accessions) and tetraploid (11 accessions). The cytogenetic evidence indicates that 2n = 2x = 22 is the diploid number and x = 11 is the base chromosome number for K. subg. Protanthium. The genome sizes among the diploid accessions ranged from 3.687 to 6.412 pg while high intraspecific variation in genome size was observed with up to 19.4%. Two species included accessions with different ploidy levels: K. rotunda L. (diploid, triploid and tetraploid) and K. takensis Boonma & Seansouk (diploid and tetraploid). The increase in genome size of tetraploid K. rotunda is nearly in correlation to the increase in ploidy level, whereas the triploid plants represent genome expansion with an approximately 11% larger than expected genome. Interestingly, tetraploid K. takensis displays genome downsizing of 15.3% compared to their diploids. The cytogenetic characteristics, together with morphology, unequivocally clarify the taxonomic status of a new species, named Kaempferia calcicola Noppornch. A revised identification key to species of K. subg. Protanthium is provided.
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    Relationship between Perceived Organizational Support, Empowerment and Organizational Commitment of Health Workers at Sub-District Health Promoting Hospitals in Suphanburi Province, Thailand
    (2024-05-01) Matvijit T.; Tadadej C.; Kittipichai W.; Matvijit T.; Mahidol University
    This cross-sectional study aims to explore the relationship between personal characteristics, perceived organizational support, empowerment, and organizational commitment. Data were collected using self-administered questionnaires from health workers at Sub-district Health Promoting Hospitals (SHPHs) in Suphanburi Province from June to July, 2023. A total of 374 out of 542 participants 69% were completed the questionnaires for data analysis. Pearson’s Product Moment Correlation Coefficient and Stepwise Multiple Regression Analysis statistics were used for data analysis. The findings revealed that most health workers perceived organizational commitment, empowerment at a moderate level (54%, 52.4%), and perceived organizational support at a high level (39.04%). Additionally, perceived organizational support, and empowerment showed statistically significant relationships with organizational commitment (r = 0.622, 0.614). Perceived organizational support and empowerment were crucial predictors accounted for 44.1% of the variance in the organizational commitment. To increase the health workers’ organizational commitment, the SHPHs supervisors should focus on improving perceived organizational support and empowerment for SHPHs to retain them within the organization.
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    Association between Personal Burnout and Depression after First Stroke of Working-age patients in Thailand: A one-year follow-up study
    (2024-01-01) Naknoi S.; Ramasoota P.; Phuanukoonnon S.; Soonthornworasiri N.; Kaewboonchoo O.; Naknoi S.; Mahidol University
    Background: Personal burnout is characterized by physical, emotional, and mental exhaustion due to prolonged stress or excessive demands. Individuals recovering from a stroke often experience significant physical and cognitive challenges during their recovery process, which can lead to increased fatigue and emotional strain. This physical and emotional exhaustion can contribute to the development or worsening of depressive symptoms. Objective: To investigate the relationship between personal burnout at baseline and depressive symptoms after stroke over one-year Methods: The study enrolled 103 participants who experienced their first stroke during working-age patients. The study period was 12 months. Personal burnout was assessed using the Copenhagen Burnout Inventory (CBI) at baseline, while depressive symptoms were measured using the Thai Hospital Anxiety and Depression Scale (HADS) at baseline, six months, and 12 months during the follow-up period. The study employed Generalized Estimating Equations to investigate the longitudinal relationship between personal burnout at baseline and depression over the course of one year. Results: High personal burnout showed a significant association with depression scores over a 1-year period, (coefficient 3.257; 95% CI: 2.299, 4.215). Conclusions: The high personal burnout score predicted worsen depressive symptoms after stoke onset. These results suggest that healthcare workers, families, and co-workers should prioritize mental health support and early detection of depressive symptoms, treatment, and coping strategies among working-age individuals who have experienced a stroke.
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    Associations between Hunger and Mental Health among Adolescents in Bangladeshi Slums Amid COVID-19
    (2024-01-01) Yasmin S.T.; Yasmin S.T.; Hong S.A.; Sultan S.; Yasmin S.T.; Mahidol University
    Objective: Identify the prevalence of hunger, anxiety, and depression, while also exploring the association between hunger, sociodemographic factors, and the presence of anxiety and depression among adolescents in Dhaka's urban slums during the Covid-19 pandemic Methods: This cross-sectional study was conducted during April to May 2022 among 324 adolescents living in slums in Dhaka division, Bangladesh. Data collection was done onsite using a structured questionnaire. Anxiety and depression were assessed using pre-validated and reliable Bangla translated versions of Generalized Anxiety Disorder (GAD-7) scale and Patient Health Questionnaire (PHQ-9). Hunger was measured using the Household Hunger Scale (HHS). Binary logistic regression was used to find associations. Results: 61.7% of the adolescents suffered from moderate – severe hunger. The prevalence of moderate to severe levels of anxiety and depression were high at 46.3% and 63.3% respectively. In logistic regression, hunger showed significant association with both anxiety (AOR= 2.345, 95% CI= 1.474-3.731) and depression (AOR= 1.852, 95% CI= 1.166-2.941). Additionally, early adolescence was associated with anxiety, and adolescents who were school going and lived in a household with >5 family members had more likelihood of both anxiety and depression. Conclusion: Hunger during the Covid-19 pandemic was associated with increased risk of anxiety and depression. In crisis situations, public health measures should ensure that poor communities have access to at least basic meals to minimize impact on mental health of adolescents. Apart from this, they should also focus on living situations in slums and enhance their efforts in the national school feeding program.
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    Developing an Application for Nursing Practice with Hypertension
    (2024-09-01) Suknark N.; Chootrakool H.; Siripitayakulkit A.; Pensiri F.; Kitidumrongsuk P.; Treewai P.; Suknark N.; Mahidol University
    To address the growing concern of hypertension in Thailand, we developed a mobile health application designed to assist patients in monitoring their blood pressure, adopting healthier behaviors, and improving self-care practices, following recommendations by the World Health Organization (WHO) to reduce modifiable risk factors. This study aims to develop and evaluate a prototype application which integrates data on blood pressure-lowering activities such as exercise routines, dietary changes, and medication adherence, with the effectiveness presented through calculated effect sizes. The application features an assessment form with multiple-choice questions to evaluate users' lifestyle habits, enabling the personalization of recommended activities based on individual needs. Guided by the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation), the prototype development involved systematic reviews and meta-analyses of nursing practices in Thailand. A quantitative online survey with four hundred and fifty-six hypertensive participants was conducted; 56.14% were male, and the majority were aged between 30 and 60 years old. Participants were selected based on specific inclusion and exclusion criteria. Satisfaction with the application was measured on a 5-point scale, with an average score of 4.45, indicating high satisfaction. Positive feedback suggests that while the prototype shows promise, further development and evaluation are needed to assess its effectiveness in reducing blood pressure and promoting healthy behaviors among hypertensive patients.
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    Systematic Review and Meta-Analysis of Diagnostic Alzheimer’s Disease with Blood Biomarkers
    (2024-05-01) Kunsanprasit N.; Chootrakool H.; Thanapluetiwong S.; Soontornpipit P.; Viwatwongkasem C.; Kunsanprasit N.; Mahidol University
    Background: One of the world's leading causes of death is Alzheimer's disease (AD). Diagnostic of the disease and determining the risk before it reaches a severe stage are essential to reduce the rate of a patient’s development into the dementia phase, as well as locating practical, economical, and effective diagnostic tools, including blood tests, are easier and still reasonably priced, compared to neuroimaging or cerebrospinal fluid (CSF) examinations. Method: The studies were systematically searched for and determined by pooled sensitivity and specificity which studies were about diagnosing AD using the single molecular array (SIMOA) method by detecting phosphorylated tau (p-tau) in the blood. In addition, Egger's test results for heterogeneity and publication bias were evaluated. Result: After systematically review the studies from 2016 to 2023, seven studies have been included for the meta-analysis. The results show low level of heterogeneity (I2 = 28.99%) and no publication bias Egger's test in sensitivity and specificity (p-value = 0.244 and 0.084, respectively) in patients. Conclusion: The ability to identify p-tau in blood with SIMOA has been useful in the diagnosis of Alzheimer's disease. Currently, this procedure is utilized in conjunction with other diagnostic approaches for diagnosis.
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    Factors Related to Mental Health and Quality of Life among College and University Teaching Professionals in Thailand
    (2024-01-01) Ratanasiripong P.; Siri S.; Hanklang S.; Chumchai P.; Galvan F.; Ratanasiripong P.; Mahidol University
    The field of higher education has grown rapidly throughout the last half-century, with student enrollment outpacing the general population growth rate in recent years. This has placed increased stress and demands upon university teaching professionals who have already been identified by researchers as one of the most stressed occupational groups. This quantitative study examined the predictors of mental health and quality of life among college and university teaching professionals. Data was collected from 360 teaching professionals employed at four higher education institutions in Thailand. Variables in this study included participants’ personal, professional, financial, health characteristics, and self-esteem as well as mental health conditions and quality of life. Multiple regression analyses revealed the following results: Gender, years work as teaching professional, BMI, and self-esteem are significant predictors of depression (adjusted R2=.33). Salary, savings, sleep, and self-esteem are significant predictors of anxiety (adjusted R2=.22). Years work as teaching professional, loans, and self-esteem are significant predictors of stress (adjusted R2=.17). Years work as teaching professional, loan, sleep, and self-esteem are significant predictors of overall quality of life (adjusted R2=.48). Preservation of university resources including teaching professionals is critical to ensuring the successful growth and development of the higher education institutions. Recommendations for improving quality of life and mental health outcomes for university teaching professionals include reducing pressure relating to research output, promoting self-esteem through mentorship and supportive workplace relationships, and encouraging healthy daily habits.
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    Characteristics of house dust mite allergens in Southeast and East Asia with the effect of hygienic practices
    (2024-06-01) Kim D.; Jeon H.; Park J.Y.; Othman H.; Thi Hien T.; Lestari P.; Tantrakarnapa K.; Lee K.; Kim D.; Mahidol University
    House dust mite allergens (HDMAs) are a major allergen that can cause severe adverse health effects, such as allergic rhinitis, asthma, and dermatitis. This study aimed to characterize the HDMA levels in bedding dust from Southeast and East Asian countries and evaluate the impact of hygiene practices on these levels. Bedding dust samples were collected from 29, 82, 32, 31, and 86 households in Indonesia, Malaysia, Thailand, Vietnam, and South Korea, respectively. Of the households in Malaysia and South Korea, 57 each had received mattress care services. The samples were analyzed for Dermatophagoides farinae type 1 (Der f1) and Dermatophagoides pteronyssinus type 1 (Der p1). The detection rates of Der f1 and Der p1 varied among the countries, especially in households that had not received mattress care services. In Indonesia, the detection rates of Der f1 and Der p1 were similar (97%). In Malaysia, Thailand, and Vietnam, the detection rates of Der f1 were higher than those of Der p1. South Korea exhibited the lowest detection rates for both Der f1 (76%) and Der p1 (7%). In Indonesia and Malaysia, the levels of Der p1 were higher than those of Der f1. In Thailand and Vietnam, the levels of Der f1 were higher than those of Der p1. In both Malaysia and South Korea, households that had received mattress care services exhibited lower HDMA levels than those that had not. Furthermore, households serviced within the past month had notably lower HDMA levels than those serviced more than two months prior. This study observed significant regional differences in the detection rates and levels of HDMAs among Southeast and East Asian nations. In addition, the study observed significant decrease in the levels of HDMAs following routine mattress care service, highlighting the pivotal role of consistent hygienic practices for diminishing potential allergenic hazards. However, the study could not identify specific regional factors affecting the type and level of HDMAs.
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    Sociodemographic and Contextual Determinants of Men’s Fertility Desires in Northern Nigeria: An Analysis of the 2018 Demographic and Health Survey
    (2024-01-01) Abbani A.Y.; Yinusa R.A.; Niazi H.; Usman M.G.; Idris U.B.; Abbani A.Y.; Mahidol University
    Nigeria has a high fertility rate, averaging 5.1 children per woman. The desire for large families, especially by men from the northern region, is a crucial driver of the country’s high total fertility rate. There is, however, a shortage of evidence on the sociodemographic determinants of men’s fertility desires despite being essential stakeholders in fertility decisions in the family. This study, therefore, estimates men’s desired family sizes and the sociodemographic and contextual factors influencing their desires in the northern region of Nigeria. Data from the men’s recoded 2018 Nigeria Demographic and Health Survey dataset were used with a sample of 7,822 men. The chi-square test and ordinal logistic regression analysis were used to test the association and estimate the relationship between the outcome and predictor variables. The findings revealed that 71% of men desired to have at least six children, which was high irrespective of sociodemographic characteristics. However, the desire for six or more children was lower (65%) among the youngest cohort than among the oldest (80%). Being a Muslim (AOR = 4.50, 95% CI [3.86, 5.24], p < .05), having two or more wives (AOR = 2.41, 95% CI [1.68, 3.45], p < .05), having 3–5 (AOR = 2.28, 95% CI [1.89, 2.76], p < .05) and six or more (AOR = 6.03, 95% CI [4.48, 8.13], p < .05) living children, and living in the northeast (AOR = 2.03, 95% CI [1.75, 2.37], p < .05) and northwest (AOR = 1.44, 95% CI [1.20, 1.72], p < .05) zones were the most significant predictors of high fertility desire by men. Policymakers should target these categories of men in fertility and family planning programs to promote lowering and slowing the rate of fertility and population growth.
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    Cultural Meanings of ‘Small:’ Similar yet Different Semantic Networks of Diminutives in Thai and South Korean
    (2024-01-01) Khammee K.; Rhee S.; Khammee K.; Mahidol University
    Lexemes denoting ‘small’ typically undergo a range of semantic or functional extensions either as free-standing lexical forms, or as weakly-grammaticalized derivational morphemes, or even fully grammatical forms. This research analyzes diminutive expressions in the two languages Thai and South Korean, following an extended ethnography of the two languages in each respective ethni0-linguistic context. Diminutives in these two languages have similarities in their source lexemes and certain developmental patterns along elegant conceptual networks. However, the two languages reveal intriguing differences in semantic extension patterns, i.e., most notably, the Thai extension pattern is ‘small therefore cute,’ whereas the South Korean extension pattern becomes one of ‘small therefore contemptible’.
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    Population-level impact of weight loss on predicted healthcare spending and the incidence of obesity-related outcomes in the Asia-Pacific region: a modelling study
    (2024-12-01) Yoong J.; Schnecke V.; Aekplakorn W.; Bandgar T.; Butt J.R.; Romano J.G.U.; Kalra S.; Khadgawat R.; Kilov G.; Kim K.K.; Lee S.Y.; Mohan V.; Proietto J.; Oldfield B.; Yoong J.; Mahidol University
    Background: The Asia-Pacific (APAC) region includes a significant proportion of the global population currently living with overweight and obesity. This modelling analysis was conducted to quantify the incidence of obesity-related comorbidities and change in obesity-related costs over 10 years with a hypothetical 10% weight loss in Australia, South Korea, Thailand, and India. Methods: An epidemiological-economic model was used to describe current prevalence and direct medical costs of ten obesity-related comorbidities, including type 2 diabetes and hypertension, in adults aged 20–69 years living with obesity, and estimate incidence and costs over 10 years. Incidence reduction and the associated savings by 2032 were then estimated for a 10% weight-loss scenario. Results: The total estimated medical costs for the ten obesity-related comorbidities in 2022 were 2.9, 7.5, 10.2, and 23.3 billion USD in Australia, South Korea, Thailand, and India, respectively. Costs increase to 6.9, 18.4, 23.5, and 44.3 billion USD in 2032, if insufficient action is taken. A 10% weight reduction would result in estimated savings of 0.3, 1.2, 2.2, and 3.0 billion USD in Australia, South Korea, Thailand, and India, respectively, in 2032, with cumulative savings over the 10-year period of 1.8, 7.0, 13.0, and 17.4 billion USD. Incidence of comorbidities were estimated to rise less in the weight-loss scenario. Conclusions: The financial, societal, and health benefits of a substantial but achievable 10% weight loss in adults living with obesity, and the consequences of insufficient action, are pronounced in the APAC region. To achieve sustained weight loss in the real world, policy actions for addressing barriers to obesity management are required.
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    Estimated global and regional economic burden of genital herpes simplex virus infection among 15–49 year-olds in 2016
    (2024-12-01) Chaiyakunapruk N.; Lee S.W.H.; Kulchaitanaroaj P.; Rayanakorn A.; Lee H.; Looker K.J.; Hutubessy R.; Gottlieb S.L.; Chaiyakunapruk N.; Mahidol University
    Background: Globally, herpes simplex virus (HSV)-2 and -1 infections contribute to a large disease burden, but their full economic consequences remain unclear. This study aims to estimate the global economic impact of genital HSV-2 and HSV-1 infection and its consequences for people with genital ulcer disease, neonatal herpes, and human immunodeficiency virus (HIV) infection attributable to HSV-2. Methods: Using a societal perspective, the economic burden was calculated at the country level and presented by World Health Organization (WHO) regions and World-Bank income levels. The disease burden was obtained from previously published global disease burden studies in 2016 and disaggregated for 194 countries. Estimates of healthcare resource utilisation were sourced from a literature review, and online interviews were conducted with 20 experts from all 6 WHO regions. Relevant costs were obtained from the literature and estimated in 2016 international dollars (I$). Results: Both genital HSV-2 (I$31·2 billion) and HSV-1 (I$4·0 billion) infections and their consequences were estimated to cost I$35·3 billion globally in 2016. The major economic burden was from the Americas and Western Pacific regions combined, accounting for almost two-thirds of the global burden (I$20·8 billion). High- and upper-middle-income countries bore a large proportion of the economic burden (76·6% or I$27·0 billion). Costs were driven by the large number of HSV-2 recurrences; however, even assuming conservatively that people with symptomatic herpes have on average only one episode a year, global costs were estimated at I$16·5 billion. Conclusions: The global costs of genital HSV infection and its consequences are substantial. HSV prevention interventions have the potential to avert a large economic burden in addition to disease burden; thus, efforts to accelerate HSV vaccine development are crucial.
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    Comparison of Ultrasonographic and Electrodiagnostic Findings Between Healthy and CTS Thais
    (2024-07-01) Puprasert C.; Ngernprasertsiri S.; Wimonwattrawatee P.; Simadamrong P.; Dacharux W.; Puprasert C.; Mahidol University
    OBJECTIVE To compare the ultrasonography cross-sectional area (CSA) of the median nerve at the wrist (CSA-D), the wrist-to-forearm median nerve CSA ratio (WFR) and the difference (WFD) between individuals with carpal tunnel syndrome (CTS) and normal individuals in the Thai population and to explore the correlation between ultrasonography and electrodiagnosis (EDX). METHODS A cross-sectional study was performed on a total of 112 wrists of 72 participants who were divided into two groups. Fifty-six wrists of 36 EDX-confirmed CTS patients were recruited as the CTS group and an equal number of individuals without CTS were chosen as a control group. Participants were matched for demographic data from a historical study. For both individuals with clinical CTS confirmed by EDX and the control population median nerve CSA levels at the wrist and at mid-forearm were measured by ultrasonography. A comparison was made between the parameters of the study group and those of the control group. The correlations between the CSA-D, the WFR, and the WFD and the severity of CTS evaluated by EDX were studied. RESULTS The mean median nerve CSA-D, WFR, and WFD of the CTS patients were 14.7 ± 5.9 mm², 3.1 ± 1.4, and 9.7 ± 6.1 mm², respectively. In contrast, the mean median nerve CSA-D, WFR, and WFD of the control group were 9.6 ± 2.4 mm², 1.7 ± 0.4, and 3.8 ± 1.9 mm², respectively, indicating a statistically significant difference from the study group (p < 0.001). The optimal cut-point values for the median nerve CSA-D, WFR, and WFD in detecting CTS were 10.7 mm² (sensitivity 67.9%, specificity 83.9%), 1.8 (sensitivity 89.3%, specificity 71.4%), and 4.7 mm² (sensitivity 82.1%, specificity 81.8%), respectively. The median nerve CSA-D, WFR, and WFD exhibited significant moderate to strong positive correlation with the EDX grading of CTS severity. CONCLUSIONS Ultrasonography of the median nerve CSA-D, WFR, and WFD are efficient for distinguishing CTS patients from asymptomatic controls with good sensitivity and specificity in the Thai population. WFD demon-strated superiority in the areas of sensitivity, specificity, and accuracy.
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    Recognition of Three Common Work-Related Hand Diseases in a Teaching Hospital
    (2024-07-01) Mitprasit A.; Aekplakorn W.; Kanchanathepsak T.; Srijareontham S.; Wongrathanandha C.; Mitprasit A.; Mahidol University
    OBJECTIVE Musculoskeletal disorders (MSDs) of the hands are increasingly affecting workers in various occupations. They reduce productivity and cause economic loss. In Thailand, work-related MSDs are considered underdiagnosed and under-reported. This study aimed to determine the proportion of three major recognized hand diseases that are work-related and to examine factors associated with that recognition and work-relatedness. METHODS This is a cross-sectional study, recruiting and interviewing patients with carpal tunnel syndrome (CTS), trigger finger (TF), and de Quervain’s tenosynovitis (DQT) aged 18-65 years old who visited the Hand Clinic in the Orthopedics Department, Ramathibodi Hospital between 25 October 2023 and 15 March 2024. Patient medical records were reviewed to determine work-relatedness using NIOSH criteria. Recognition was determined by taking patient work histories. Logistic regression was used to examine the associations between work and MSDs, and between recognition and patients’ factors. RESULTS A total of 270 patients were included: 127 CTS cases, 96 TF cases, and 47 DQT cases. Almost two-thirds (63.0%) of the diseases were attributed to work-related conditions. Factors associated with workrelatedness of the three diseases were: working for 26 or more hours per week (adjusted ORs 3.26-4.63), tool use (ORadj 7.92, 95%CI [2.83, 22.17]), computer use (ORadj 4.72, 95%CI [1.84,12.14]), writing (ORadj 4.88, 95%CI [1.53, 15.61]), and having a single job (ORadj 10.13, 95%CI [2.59,39.57]). The proportion of recognition by physicians of the connection between working history and MSDs was only 13.0%. There were no significant associations between patients’ personal/work factors and recognition by doctors. CONCLUSIONS This study showed that 63.0% three common hand diseases of patients are attributed to work-related conditions, but the recognition by doctors of that relationship was only 13.0%. Factors associated with work-relatedness were mostly aspects of patients’ work. The hospital should improve its system for identifying the work-related MSDs to help ensure patients receive appropriate health-related welfare and benefits. Further studies should be conducted to explore means of increasing physician recognition of work-related MSDs.
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    A Eulogy for His Majesty King Buddha Lert La Nabhalai Through the Literature Record of a Coronation Ceremony in the Rattanakosin Period
    (2024-06-01) Dangsakul K.; Theekaprasertkul P.; Dangsakul K.; Mahidol University
    Background and objective [S]: A Eulogy for His Majesty King Buddha Lert La Nabhalai was composed by Phra Nangklao Chaoyuhua (King Rama III). The literature has been categorized as eulogistic literature since it contained common characteristics of literature that praises a king. However, this literature has outstanding characteristics to distinguish it from other eulogy literature, especially the content that records the events of the coronation of King Rama II in its entirety through a literary manner. Therefore, the researcher is interested in using this literature to study according to the concept of genre theory. The objective of this study was to examine the specific characteristics of A Eulogy for His Majesty King Buddha Lert La Nabhalai and to investigate whether it can be classified as a literature record of a coronation ceremony in the Rattanakosin period. This study portrays the value of this literature in the aspect of coronation record literature and is useful for further study of the classification of Thai literature. Methodology: This study was qualitative research analyzing literary data according to the objectives of the study by considering the concept of literature classification, along with the body of knowledge about coronation ceremonies, presenting the results of the study in an analytical descriptive manner. Findings: A Eulogy for His Majesty King Buddha Lert La Nabhalai contained five key characteristics: 1) The eulogy was recorded based on the author’s experience who attended the royal ceremony. 2) The eulogy included background knowledge of the coronation ceremony and demonstration of the legitimate right in the accession of the monarch. 3) The eulogy recorded the main process of conducting the coronation ceremony. 4) The eulogy specified the place, people and equipment used in the ceremony completely. 5) The eulogy conveyed narration of the event and atmosphere, along with the feeling of appreciation of the participants in the ceremony. Moreover, literary techniques used were outstanding in terms of prosody in klong type of poetry, leading to sounds and rhythms while reading, as well as the selection of literary language, including both word selection and metaphor usage to describe the atmosphere of the ceremony and the sentiment. Consequently, this literature contains the specific characteristics of the recording of a royal ceremony that was different from other types of recordings, such as royal chronicles that often employed language to describe stories rather than depicting images and sentiments. According to the above specific characteristics, this literature was meticulously written with literary value and can be classified as a literature record of a coronation ceremony. Relevance to Thai Studies: This study is a key guideline for studying the classification of Thai literature. The research examines the relationship between the creation of literature and the coronation ceremony through Thai literary tradition. This also enhances knowledge about the coronation ceremony of King Buddha Lert La Nabhalai and the history of Thai literature in the Rattanakosin period. Conclusion: A Eulogy for His Majesty King Buddha Lert La Nabhalai is not only valuable literature as a eulogy, but also valuable as a literary record of the coronation ceremony. This literature was composed directly from the content of the coronation of King Buddha Lertla Nabhalai with the harmony of praise of the king in a literary manner. It is worth noting that some literature in later periods was also composed in the same way as this literature. For example, in Khlong Lilit Suphap Tamrap Phraboromrachaphisek Sapdama Ratcha Maha Chakkriwong B.E.2468, the coronation ceremony of King Prajadhipok (King Rama VII) was recorded in detail. It could be considered that A Eulogy for His Majesty King Buddha Lert La Nabhalai was a key starting point for the composition of the literature record of coronation ceremonies, resulting in the creation of the same characteristic of this literature that was more concrete and clearer in the later period.
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    Comparison of Blood and Urinary Cannabis Profiles Between Road Traffic Injury (RTI) and Other Causes of Death in Thai Postmortem Cases
    (2024-07-01) Charatprakai P.; Sukata S.; Phuangphung P.; Charatprakai P.; Mahidol University
    OBJECTIVE This study aims to compare blood and urinary cannabis profiles between road traffic injury (RTI) and other unnatural causes of death in the Thai population. METHODS A cross-sectional study was conducted of Thai postmortem cases where the individual who died was 15 years old or over. Sex, age, cause of death, manner of death, blood alcohol concentration (BAC), and concomitant drugs found were documented for each case. Blood and urinary concentrations of delta 9-tetrahydrocannabinol (THC) and its two metabolites, 11-hydroxy-delta 9-tetrahydrocannabinol (11-OH-THC) and 11-nor-9-carboxy-delta 9-tetrahydrocannabinol (THC-COOH), were analyzed using gas chromatography tandem mass spectrometry (GCMS/MS). Statistical analysis was performed using the Mann-Whitney U test and Kruskal-Wallis H test. RESULTS A total of 80 subjects were included in this study, comprising 43 RTI and 37 non-RTI subjects. All the RTI cases were motorcycle riders. Blood concentrations of THC, 11-OH-THC, and THC-COOH in the RTI group were significantly higher than those in the non-RTI group (p < 0.01). The number of subjects who had recent cannabis exposure in the RTI group was significantly higher than in the non-RTI group (p< 0.05). Furthermore, the blood concentrations of THC, 11-OH-THC, and THC-COOH in subjects who used cannabis without other drugs of abuse or medications were significantly higher than those in subjects who used cannabis with other drugs of abuse or other medications (p < 0.05). CONCLUSIONS Blood THC, 11-OH-THC, and THC-COOH concentrations in RTI cases were significantly higher than in cases with other unnatural causes of death.
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    Public Expressions of Religion among Yogyakarta's Salafi Muslimah
    (2024-12-22) Marhumah; Muyassaroh I.K.; Sciortino R.; Marhumah; Mahidol University
    This study examines the manifestation of righteousness in public spaces among Salafi Muslim female students participating in Islamic study groups at four major universities in Yogyakarta, Indonesia. Using a qualitative case study approach, data were collected through six months of participant observation and in-depth interviews with eight key informants. The research explores how Salafi Muslim women internalize, negotiate, and practice hadith teachings daily, particularly in public settings. The findings reveal that these study groups significantly shape individual and collective expressions of piety. Participants exhibit varied approaches to negotiating religious teachings, with some finding clarity and structure, while others experience ambiguities, creating space for personal interpretation. This variation underscores the complex relationship between religious texts and individual agency, aligning with theoretical perspectives on spiritual practice. Additionally, the study highlights the importance of these groups in reinforcing social identities and facilitating engagement in public spaces. The research contributes to broader discussions on religious agency and public piety, providing insights into how Salafi Muslim women navigate the intersection of spiritual devotion and modern public life. Limitations include the focus on a specific group and reliance on self-reported data. Future studies should explore how piety is expressed across social and cultural contexts to deepen understanding of its role in public participation.