Scopus 2024
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Item Metadata only Reliability and Validity of a Thai Version of a Modified Frenchay Activities Index for Use with Stroke Patients(2024-09-01) Triloga N.; Harnphadungkit K.; Tantisuvanitchkul P.; Triloga N.; Mahidol UniversityObjectives: To evaluate the reliability and validity of the Thai version of the modified Frenchay Activities Index (mFAI) ques-tionnaire for use with stroke patients Study design: Descriptive study Setting: Department of Rehabilitation Medicine and Neurology Division, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand Subjects: Stroke patients visiting the Outpatient Department of the Rehabilitation Medicine and Neurology Division, Department of Medicine, from March 2020 to August 2020 Methods: Data were collected using a Thai version of the modified Frenchay Activities Index (Thai-mFAI). Of 75 patients, 70 met the inclusion criteria. After the initial assessment, all 70 participants were reassessed 3-7 days later to determine test-retest reliability. Validity was assessed from 59 participants by evaluating the correlation between the Stroke Impact Scale (SIS) and the Timed Up-and-Go test (TUG). Results: The Thai-mFAI showed good content validity (CVI = 0.95), fair construct validity (convergent validity; r=0.287-0.310, discriminant validity; r=-0.259), excellent test-retest reliability (ICC3,1=0.929) and excellent internal consistency (Cronbach’s alpha = 0.936). Conclusions: The Thai-mFAI was found to have good content validity, fair construct validity, excellent test-retest reliability, and excellent internal consistency. These suggested that Thai-mFAI is suitable for evaluating how well active stroke patients can per-form activities of daily living.Item Metadata only An Observational Longitudinal Study Investigating the Effectiveness of Adjustable Splint on Individuals with Hallux Valgus(2024-01-01) Chadchavalpanichaya N.; Limsapjaroen J.; Suwannakin A.; Chadchavalpanichaya N.; Mahidol UniversityObjectives: To explore the effectiveness of an adjustable splint to decrease hallux valgus angle and pain at the first metatarso-phalangeal joint. In addition, to discover complications and parti-cipants’ satisfaction Study design: Prospective cohort analytical study design Setting: Foot Clinic, Department of Rehabilitation Medicine, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand Subjects: Thirty-eight patients with hallux valgus deformity at moderate to severe degrees (hallux valgus angle 30°-50°) were recruited from March to May 2021. Methods: The participants were asked to use an adjustable splint for 6 hours daily for 12 months and continue their current treatment regimen. They were also asked to record the duration of wearing the splint and complications in a logbook every week. Hallux valgus angle measured from radiography and pain numeric rating scale (pain NRS) were evaluated at baseline, 6 months, and 12 months after getting the splint. Results: Thirty-two participants returned for follow-up at the end of the study. Per protocol and intention to treat, analyses showed a decreased hallux valgus angle and pain at the first metatarso-phalangeal joint with a statistically significant difference (p = 0.001). The satisfaction scores with the adjustable splint were high in every domain. No participant had serious complications. The common complication was splint slip (33.3%). Conclusions: Wearing an adjustable splint for 12 months in patients with moderate to severe degrees of hallux valgus could decrease hallux valgus angle and pain at the first metatarso-phalangeal joint without serious complications.Item Metadata only Factors Contributing to Cardiac Rehabilitation Uptake Among Patients with Coronary Artery Disease in Thailand: A Nationwide Cross-Sectional Study(2024-01-01) Kotcharoen R.; Tower M.; Boyde M.; Eley R.; Kotcharoen R.; Mahidol UniversityObjectives: This study aimed to identify factors contributing to cardiac rehabilitation (CR) uptake among patients with coronary artery disease (CAD) in Thailand. Study design: A descriptive survey study Setting: Data collection took place at an urban and a rural hospital. Subjects: Patients were eligible for the study if they had been referred for CR by the medical staff during their in-patient stay. Methods: Data were collected from June 2018 to July 2019. Patients with CAD attending either the urban or the rural hospital completed the Cardiac Rehabilitation Barriers Scale (CRBS) questionnaire which surveyed barriers to CR uptake. Results: The mean age of the 138 respondents was 64 years with 68.8% aged 60 or older; 70% were male, and 67.4% were CR attendees. Patients aged 60-69 were found to have the highest uptake of CR. Rural patients with CAD differed from those from urban areas in having a lower level of education (X2 (2, n = 67) = 14.58, p = 0.001, phi= 0.466) and lower family income (X2 (2, n = 67) = 9.60, p = 0.008, phi = 0.379). Rural patients with fewer years of formal education and those who were farmers were less likely to attend CR. Rural patients reported more barriers to CR than did urban participants. The main barriers to CR uptake for rural patients were distance from and transportation to the clinic. Conclusions: While the existing CR hospital-based programs in Thailand may be appropriate for urban patients with CAD, they are less useful for patients living in rural areas. Existing CR programs should be modified to include more nuanced approaches to CR suitable for rural patients.Item Metadata only A Preliminary Report of the Effects of Dharma Creative Art Therapy on Psychological Impacts and Quality of Life of Thai Cancer Patients: A Non-Randomized Trial(2024-09-01) Jutakeo J.; Kuptniratsaikul V.; Limampai P.; Akewanlop C.; Hantaweepant C.; Thephamongkhol K.; Yaimanee P.; Jutakeo J.; Mahidol UniversityObjectives: To determine the effects of Dharma Creative Art Therapy (CAT) on psychological impacts and quality of life Study design: Non-randomized trial Setting: Department of Medicine, Siriraj Hospital Subjects: Cancer patients during chemotherapy Methods: This preliminary study recruited eighty-two patients into an experimental group which participated in a 90-minute Dharma CAT session for two consecutive days, while the control group received only a leaflet on holistic approach of cancer palliative treatment. Psychological outcomes of the Dharma CAT were measured using the Hospital Anxiety and Depression Scale (HADS), the Thai Stress Test (TST), the Thai Mental Health Index-15 (TMHI-15), and the EQ-5D-5L, which were evaluated before, immediately after, and one month after the intervention. Results: After the intervention, the CAT group had significantly improved positive TST and TMHI-15 scores compared to the control (p=0.006 and p=0.018, respectively). The effect size of Dharma CAT on positive TST was moderate (0.568) and was minimal for TMHI-15 (0.373). The success rate of patients after receiving Dharma CAT therapy on anxiety, depression, stress, and mental health presented with a relative risk (RR) of 3.0 (95CI: 0.64, 14.00), 1.5 (95CI: 0.46, 4.92), 2.5 (95CI: 0.85, 7.33), and 0.8 (95CI: 0.23, 2.77), respectively but the changes were not statistically significant. All outcomes were analyzed and compared between groups at baseline, at the end of the study, and at the 1-month follow-up. No statistically significant differences between the groups for any of the outcomes were found. Conclusions: Dharma CAT reduces stress and improves mental health but does not affect anxiety, depression, or quality of life. It may be considered an adjunctive therapy for reducing stress and improving mental health of cancer patients during chemotherapy.Item Metadata only Factors Related to Quality of Life in Patients with Carpal Tunnel Syndrome: A Cross-Sectional Study(2024-08-01) Phitsa-Ard R.; Harnphadungkit K.; Phitsa-Ard R.; Mahidol UniversityObjectives: To determine the association between the quality of life (QoL) of patients diagnosed with carpal tunnel syndrome (CTS) by electrodiagnostic study (EDX) and CTS severity, as well as to identify other associated factors Study design: Cross-sectional study Setting: Department of Rehabilitation Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University Subjects: A total of 140 CTS participants diagnosed by EDX including patients aged 18 or over, who were able to communicate in Thai, were fully conscious, and were willing to participate in this research. Methods: Participants were recruited and asked to complete the questionnaire about demographic and clinical characteristics related to CTS, the Boston questionnaire (Thai version), the Thai version of the Hospital Anxiety and Depression Scale (Thai HADS), and the EQ-5D-5L questionnaire. The data from questionnaires and the EDX results were collected and analyzed. Results: Utility scores of the EQ-5D-5L questionnaire were correlated with Boston functional severity score (FSS) (r =-0.603, p < 0.001), Boston symptom severity score (SSS) (r =-0.546, p < 0.001), and anxiety (p=0.004). The electrophysiological severity had no association with patients’ QoL (rs = 0.079, p = 0.354). Health visual analog scale (VAS) scores were correlated with anxiety, Boston functional severity score, and leisure activity. Other factors studied, e.g., age and income, were not associated with the patient’s QoL. Conclusions: CTS patients’ QoL is correlated with the subjective symptom severity, functional severity, anxiety, and the inability to participate in leisure activities, but not electrophysiologic severity.Item Metadata only Hardware and Software Design for the TSC-1 Payload Flat-sat Platform: Hyperspectral Imaging and Space Particle Particle Weather Detection(2024-01-01) Khongprasongsiri C.; Kitiphuwadon N.; Boonnun N.; Piluntasopon S.; Burom S.; Phattanarat N.; Areerob P.; Chaiwongkhot K.; Vongsantivanich W.; Saisutjarit P.; Khongprasongsiri C.; Mahidol UniversityThe TSC-1 project, a pioneering scientific endeavor by Thailand, focuses on hyperspectral imaging and the detection of space particle weather. Currently in the development phase, the project involves comprehensive validation and testing to ensure that the satellites functionalities meet the requisite standards. A crucial component of this phase is the development of a dedicated flat-sat platform. Specifically, the TSC1 payload flat-sat incorporates a CMV4000 image sensor coupled with a Xilinx Zynq MPSoC electronic circuit board for hyperspectral imaging, and an LTC2265 Analog-to-Digital converter for space weather readout procedures. To store and transmit scientific data, the data handling unit built with NAND memory and the EnduroSat X-band transmitter is attached. In addition, in-payload communication software, designed to transmit commands and data to the ground via the data handling unit, is a key focus of software testing. Both hardware and software are built as a platform, making the design reusable. This platform is specifically designed to facilitate efficient testing and rapid debugging of the core satellite functionalities. By enabling seamless electrical connections among the TSC-1 payload components and ensuring accessibility to key interfaces for bus system connectivity and testing apparatus, the flat-sat platform significantly enhances the testing process. This paper demonstrates the design and elaborate of the payload flat-sat, the data transfer capability utilizing the robust protocol, power consumption, and also specified mission planning based on the results of the experiment to ensure the maximum advantage of the satellite.Item Metadata only Facilitators and Barriers to Cardiac Rehabilitation Uptake Among Patients with Coronary Artery Disease in Thailand: A Qualitative Study(2024-05-01) Kotcharoen R.; Tower M.; Boyde M.; Eley R.; Kotcharoen R.; Mahidol UniversityObjectives: This study explored factors affecting cardiac rehabilitation (CR) uptake among patients with coronary artery disease (CAD) in Thailand. Study design: An exploratory qualitative design Setting: Data collection was conducted at two CR centers, one in an urban hospital and one in a remote hospital. Subjects: CR healthcare providers (HPs) and patients with CAD who had been referred for CR by medical staff during their in-patient stay. Methods: An exploratory qualitative research design using semi-structured interviews of 20 patients and 22 HPs was employed. Data were collected from June 2018 to July 2019. Transcribed interview data were analyzed thematically. Results: The common themes identified by patients and HPs that contributed to uptake of CR included culture and religion, as well as social, logistical, and educational themes. Knowledge of CR and its benefits also facilitated attendance. Both groups recognized commitments to family and work as barriers to CR. Both groups also perceived that they had misconceptions about CR exercise programs and inaccurate communication regarding CR as barriers to CR attendance. Importantly, high respect for doctors as well as Buddhist beliefs and practices were cultural factors mentioned by patients as important enablers of CR. Notably, this is the first study in Thailand to identify feeling safe attending CR as being a major enabling factor for CR uptake. Conclusions: Religious and cultural factors impact the uptake of CR among patients with CAD in Thailand. Creation of culturally-based CR programs should be considered a priority, as should identifying potential approaches to successful delivery of CR in rural areas of the country.Item Metadata only Efficacy of Rhythmic Auditory Stimulation on Balance in Children with Cerebral Palsy: A Randomized Controlled Trial(2024-01-09) Panompornpanich A.; Sanjaroensuttikul N.; Iamchaimongkol A.; Panompornpanich A.; Mahidol UniversityObjectives: Evaluate efficacy of rhythmic auditory stimulation (RAS) on balance in children with cerebral palsy. Study design: Randomized controlled trial Setting: Sri-Sangwan School, Bangkok, Thailand Subjects: Children with cerebral palsy, GMFCS levels I to III Methods: Participants were randomly allocated into RAS and control groups. All participants underwent a physical therapy involving exercises and gait training for 3 weeks. RAS group received gait training with RAS. We measured Timed Up and Go-In Children (TUG-IC), Pediatric Balance Scale (PBS), Gross Motor Function Measure (GMFM-66), and gait velocity. Results: 22 cerebral palsy aged 7-15 years were divided into control and RAS, 11 participants per group. Results revealed improvement of TUG-IC, PBS, and GMFM-66 in both groups. The median (95% CI) difference between before and after training of TUG-IC were 1.51 (-16.35, 21.77) second in control and 0.90 (-29.38, 25.76) second in RAS. The differences in PBS were 1.5 (0.03-3.96) in control and 1 (-3.84, 1.84) in RAS. The change of GMFM-66 was 3.5 (0.38, 5.61) in control and 3 (-3.78, 3.78) in RAS. Whereas gait velocity only increased in control group. RAS showed no statistically significant improvement in TUG-IC, PBS, and GMFM-66. While control group only significantly increased PBS and GMFM-66 (p = 0.047, p = 0.027), no significant difference in TUG-IC or gait velocity. Comparison between RAS and control revealed no significant difference in TUG-IC, PBS, GMFM-66, or gait velocity. Conclusions: The addition of RAS to physical therapy may not improve efficacy of training beyond effects of physical therapy alone.Item Metadata only Psychology in Thailand(2024-01-01) Lertgrai W.; Rhein D.; Lertgrai W.; Mahidol UniversityThe issue of mental health in Thailand has a long history with records that date back over 200 years to a time when mental abnormality was treated by exorcizing demons and treatments were inscribed onto temple walls. At present, the role of psychologists is becoming more recognizable through academic and social means, although many are still confused about the respective roles of psychologists and psychiatrists. Furthermore, most subfields of Thai psychology remain unregulated apart from the clinical field, which has licensure. The job descriptions of most psychologists remained vague and broad, adding to the public’s confusion. Future standardizations of the profession will help Thai psychologists to be recognized at local and international levels.Item Metadata only Probiotic Regulations in Asian and Australasian Countries(2024-01-01) Lee Y.K.; Xu J.; Han X.; Singh J.; Surono I.S.; Tanaka H.; Park M.S.; Ji G.E.; Tee E.S.; Tan J.D.; Elegado F.; Tan Y.L.; Chen M.J.; Jirawongsy M.; Santivarangkna C.; Vinh L.H.; Gray C.; Lee Y.K.; Mahidol UniversityThe guidelines for probiotic products in Asian and Australasian countries are not harmonized; each country has unique product regulations. Some are restrictive, whereas others are elaborate and specific. This chapter summarizes probiotic regulations in 13 Asia and Australasia regions and countries, namely China, India, Indonesia, Korea, Malaysia, Philippines, Singapore, China, Taiwan, Thailand, Vietnam, Australia, and New Zealand in some details, and thus serve as an comprehensive reference.Item Metadata only Role of trigonelline, a bioactive alkaloid in coffee, for kidney stone prevention(2024-01-01) Peerapen P.; Thongboonkerd V.; Peerapen P.; Mahidol UniversityTrigonelline is one of the major bioactive alkaloids in coffee. Beneficial effects of trigonelline have been widely reported in several diseases, including Alzheimer's disease and diabetes. For the kidney, trigonelline exhibits several renoprotective effects, including antioxidative, antiinflammatory, antiapoptotic, and antifibrotic activities. In kidney stone disease (nephrolithiasis), consumption of either caffeinated or decaffeinated coffee is associated with the stone risk reduction. The beneficial role of trigonelline against kidney stone disease has been demonstrated in a number of in vivo and in vitro studies. For example, the antilithiatic effect of aqueous extract from fenugreek seeds (rich with trigonelline) has been demonstrated in rats with calcium oxalate (CaOx) kidney stone induced by ethylene glycol. Such antilithiatic effect of trigonelline is most likely due to its inhibitory activities against CaOx crystallization, crystal growth, and crystal adhesion on renal tubular epithelial cells, all of which are the important processes for CaOx kidney stone formation.Item Metadata only Formulation Development of Serum Beads: Investigating the Influence of Sodium Alginate/Iota Carrageenan Ratio on Bead Characteristics(2024-05-01) Woraphokanunt Y.; Teeranachaideekul V.; Rittiboon A.; Jatupornpipat M.; Woraphokanunt Y.; Mahidol UniversityBackground and Objectives: To develop cosmetic products by using Ionic gelation techniques as the main technique in the production of serum beads. The purpose of this study is to develop the serum beads recipe by studying the ratio of various types of gelling agents for complete serum beads products. Methodology: Test the ratio of gelling agents in serums that create beads with ionic gelation techniques by Sodium Alginate and Iota-carrageenan which affect the appearance and beads texture after forming. Then compare the concentration of the gelling agent used in the suspension of serum beads that affects the ability to suspend serum beads. In this study, Carbopol® ultrez 20 was selected as the type of gelling agent. Main Results: The most suitable ratio for forming serum beads between Sodium Alginate and Iota-carrageenan is 0.20:0.30. Because the appearance of serum beads is spherical which can be pressed, cracked and spread on the surface easily-moderately, which is the most suitable characteristic for serum beads compared with the other ratios. When the serum beads were suspended inside the Carbopol® ultrez 20 gel at different concentrations and sensory tests, it was found that Carbopol® ultrez 20 at a concentration of 0.70 percent was the most favored. After storing in accelerated conditions to test the stability of the product, it was found that all concentrations of the gelling agent Carbopol® ultrez 20 could make the serum beads suspended and disperse inside the gel, but the viscosity was significantly reduced in each formulation. Conclusions: Conclusion: The ratio of Sodium Alginate and Iota-carrageenan affects the formation and hardness of beads. The most suitable ratio in this study is 0.20:0.30 and the gelling agent Carbopol® ultrez 20 at a concentration of 0. 70 percent is the most suitable choice for using as a suspension gel in the serum bead cosmetic formula. Because it is the most stable and has the least change when stored in accelerated condition for 8 weeks.Item Metadata only The Grammar of Science: Chance and Magnitude(2024-01-01) Kaewkungwal J.; Kaewkungwal J.; Mahidol UniversityItem Metadata only Prevalence of Depressive Symptoms and Associated Factors among Cross Border Migrants in Thailand, 2023: a Mixed-methods Study(2024-10-01) Sikhiwat N.; Rajsiri K.; Nunes J.; Uansri S.; Panapong N.; Kunpeuk W.; Adhibai R.; Wongsuwanphon S.; Suphanchaimat R.; Sikhiwat N.; Mahidol UniversityDepression is a significant global health issue, and migrants often face barriers to mental health care, resulting in undiagnosed depressive symptoms. Thailand accommodates many cross-border migrants from Cambodia, Lao PDR, and Myanmar (CLM), yet little is known about depressive symptoms in these populations. This study aims to address this gap. A mixed-methods study was therefore conducted to assess the prevalence of depressive symptoms and determine associated factors. Quantitative data were collected via a paper-based questionnaire, including the Patient Health Questionnaire-9 (PHQ-9), and analyzed using multiple logistic regression. Qualitative data from in-depth interviews were analyzed using content analysis. Of the 431 participants, who were mostly female (73.3%) and from Myanmar (97.9%), the prevalence of depressive symptoms was 23.9%. Having public insurance (adjusted odds ratio (AOR) 0.24, 95% confidence interval (CI) 0.13– 0.43) and being employed (AOR 0.33, 95% CI 0.19–0.57) were significant protective factors. Alcohol consumption showed no association with depression. Qualitative findings reinforced the protective role of public insurance and highlighted employment as a critical factor in mental well-being. These results underscore a notable prevalence of depressive symptoms among CLM migrants, emphasizing the need for health policies that increase access to mental health care and support for this population. Further research should explore broader mental health factors among migrants to guide comprehensive policy development.Item Metadata only The Grammar of Science: Good Design of Data Collection Form—a Must-do(2024-04-01) Kaewkungwal J.; Kaewkungwal J.; Mahidol UniversityItem Metadata only The Grammar of Science: It’s All about Trustworthiness of Your Data(2024-07-01) Kaewkungwal J.; Kaewkungwal J.; Mahidol UniversityItem Metadata only THE SECOND RECORD OF A FIRETHROAT CALLIOPE PECTARDENS IN THAILAND(2024-01-01) Round P.; Jearwattanakanok A.; Walser-Schwyzer P.; Khudamrongsawat J.; Round P.; Mahidol UniversityThe second record of an apparently over-wintering Firethroat Calliope pectardens (Muscicapidae) in northern Thailand, a female, caught and ringed following its discovery, is documented. Reference is made to a previous Thai record of the Firethroat’s sister species, the Blackthroat C. obscura. Since the females of both species are very similar, the identity of the present individual was confirmed both by examination in the hand and by DNA assay. The importance of maintaining marginal lowland habitats, such as scrub and reeds along the banks of lowland watercourses and around field margins, so as to maintain biodiversity in intensively agricultural lowland landscapes, is discussed.Item Metadata only Lasers for the Treatment of Pigmentary Disorders(2024-01-01) Lizarondo F.P.J.; Manuskiatti W.; Lizarondo F.P.J.; Mahidol UniversityPigmentary disorders of the skin are a heterogenous complex set of skin diseases that share a common pathology of increased melanin deposition. While most of these disorders can be treated with topical agents and surgery, lasers and energy-based devices (EBDs) have emerged as a preferred treatment modality. Lasers have become the gold standard in treating nevus of Ota and acquired nevus of Ota-like macules (ABNOMs) or Hori nevus. Lasers that are pigment specific primarily work by targeting the chromophore melanin contained in the melanosomes. Since these structures are small and have very short thermal relaxation times, lasers with pulse durations in the nanosecond and picosecond range are ideal for minimally invasive pigment removal.Item Metadata only Neuromuscular and Electrodiagnostic Medicine Board Review, 1st Edition(2024-01-01) Thammongkolchai T.; Termsarasab P.; Katirji B.; Preston D.C.; Thammongkolchai T.; Mahidol UniversityThe only review book currently available in this complex field, Neuromuscular and Electrodiagnostic Medicine Board Review is an all-in-one, must-have resource for preparing for the neuromuscular and electrodiagnostic medicine, neurology, clinical neurophysiology and physical medicine and rehabilitation board exams. Focused, high-yield content is provided in a concise, readable manner without exhaustive or unnecessary detail, helping you make the most of your study time and efficiently prepare for exams and clinical practice.Item Metadata only Can the International Court of Justice Shape Global Climate Action Through Law, Authority, and Accountability?(2024-07-01) Novita A.; Lestari E.; Sanni T.; Min Z.; Arifin R.; Srisawat K.; Novita A.; Mahidol UniversityClimate change presents an unprecedented challenge to the international legal order, raising urgent questions about responsibility, compliance, and enforcement. This article examines whether the International Court of Justice (ICJ) can meaningfully shape global climate action through its legal authority and judicial functions. It analyzes the Court’s potential role in clarifying states’ obligations under international law, particularly in relation to environmental protection, human rights, and the principle of due diligence. By assessing both contentious cases and advisory opinions, the article explores how the ICJ may influence state behavior even in the absence of direct enforcement mechanisms. The study situates the ICJ within the broader framework of international climate governance, including treaties such as the United Nations Framework Convention on Climate Change and the Paris Agreement. It evaluates how the Court's interpretations of customary international law, state responsibility, and transboundary harm could contribute to greater legal accountability for climate-related conduct. Particular attention is given to the growing momentum behind climate litigation and recent initiatives seeking advisory opinions on states' climate obligations. While acknowledging institutional limitations-such as jurisdictional constraints, state consent, and political resistance the article argues that the ICJ possesses significant normative power. Its judgments and opinions can shape legal discourse, influence domestic courts, and strengthen the legitimacy of climate obligations under international law. Ultimately, the article contends that the ICJ can play a transformative, though indirect, role in global climate action by reinforcing legal standards, enhancing accountability, and contributing to the development of a coherent international response to climate change.