Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial
Issued Date
2022-08-01
Resource Type
ISSN
16617827
eISSN
16604601
Scopus ID
2-s2.0-85135372014
Pubmed ID
35897363
Journal Title
International Journal of Environmental Research and Public Health
Volume
19
Issue
15
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Environmental Research and Public Health Vol.19 No.15 (2022)
Suggested Citation
Phonghanyudh A., Duangthip D., Mabangkhru S., Jirarattanasopha V. Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial. International Journal of Environmental Research and Public Health Vol.19 No.15 (2022). doi:10.3390/ijerph19158992 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/84693
Title
Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial
Other Contributor(s)
Abstract
Background: There is limited information on the effectiveness of 38% silver diamine fluoride (SDF) in managing enamel caries. Objective: This study aimed to compare effectiveness of 38% SDF and 5% Sodium fluoride (NaF) varnish in arresting enamel caries in young children when applied semiannually over 18 months. Methods: A randomized controlled trial was conducted on children aged 1–3 years who had at least one active carious surface. They were allocated into two groups: Group 1 (38% SDF) and Group 2 (5% NaF varnish). Visual-tactile examination was used to assess extent of carious lesions. Enamel caries that did not progress to dentin were classified as having caries arrest. Intention-to-treat analysis was performed. Results: At baseline, 290 children with 1974 tooth surfaces with enamel caries were recruited. Caries arrest rates at the tooth surface level in Group 1 and Group 2 were 59.1% and 58.8%, respectively (p = 0.873), at 18 months. The multilevel logistic regression analysis revealed that tooth position, tooth surface, extent of enamel caries at baseline, caries experience, and brushing with fluoride toothpaste influenced caries arrest (p < 0.05). Conclusion: The semiannual application of 38% SDF and 5% NaF varnish had comparable effectiveness in arresting enamel caries in primary teeth.