Comparative genomics and genome-wide SNPs of endangered Eld’s deer provide breeder selection for inbreeding avoidance
Issued Date
2023-12-01
Resource Type
eISSN
20452322
Scopus ID
2-s2.0-85176331558
Journal Title
Scientific Reports
Volume
13
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
Scientific Reports Vol.13 No.1 (2023)
Suggested Citation
Pumpitakkul V., Chetruengchai W., Srichomthong C., Phokaew C., Pootakham W., Sonthirod C., Nawae W., Tongsima S., Wangkumhang P., Wilantho A., Utara Y., Thongpakdee A., Sanannu S., Maikaew U., Khuntawee S., Changpetch W., Phromwat P., Raschasin K., Sarnkhaeveerakul P., Supapannachart P., Buthasane W., Pukazhenthi B.S., Koepfli K.P., Suriyaphol P., Tangphatsornruang S., Suriyaphol G., Shotelersuk V. Comparative genomics and genome-wide SNPs of endangered Eld’s deer provide breeder selection for inbreeding avoidance. Scientific Reports Vol.13 No.1 (2023). doi:10.1038/s41598-023-47014-x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/91119
Title
Comparative genomics and genome-wide SNPs of endangered Eld’s deer provide breeder selection for inbreeding avoidance
Author(s)
Pumpitakkul V.
Chetruengchai W.
Srichomthong C.
Phokaew C.
Pootakham W.
Sonthirod C.
Nawae W.
Tongsima S.
Wangkumhang P.
Wilantho A.
Utara Y.
Thongpakdee A.
Sanannu S.
Maikaew U.
Khuntawee S.
Changpetch W.
Phromwat P.
Raschasin K.
Sarnkhaeveerakul P.
Supapannachart P.
Buthasane W.
Pukazhenthi B.S.
Koepfli K.P.
Suriyaphol P.
Tangphatsornruang S.
Suriyaphol G.
Shotelersuk V.
Chetruengchai W.
Srichomthong C.
Phokaew C.
Pootakham W.
Sonthirod C.
Nawae W.
Tongsima S.
Wangkumhang P.
Wilantho A.
Utara Y.
Thongpakdee A.
Sanannu S.
Maikaew U.
Khuntawee S.
Changpetch W.
Phromwat P.
Raschasin K.
Sarnkhaeveerakul P.
Supapannachart P.
Buthasane W.
Pukazhenthi B.S.
Koepfli K.P.
Suriyaphol P.
Tangphatsornruang S.
Suriyaphol G.
Shotelersuk V.
Author's Affiliation
Siriraj Hospital
Khaokeaw Open Zoo
Zoological Park Organization, Bangkok
Chulalongkorn University
Conservation and Research Center (National Zoo)
King Chulalongkorn Memorial Hospital
George Mason University
Thailand National Center for Genetic Engineering and Biotechnology
Faculty of Medicine, Chulalongkorn University
Zoological Park Organization of Thailand
Zoological Park Organization of Thailand
Khaokeaw Open Zoo
Zoological Park Organization, Bangkok
Chulalongkorn University
Conservation and Research Center (National Zoo)
King Chulalongkorn Memorial Hospital
George Mason University
Thailand National Center for Genetic Engineering and Biotechnology
Faculty of Medicine, Chulalongkorn University
Zoological Park Organization of Thailand
Zoological Park Organization of Thailand
Other Contributor(s)
Abstract
Eld’s deer, a conserved wildlife species of Thailand, is facing inbreeding depression, particularly in the captive Siamese Eld’s deer (SED) subspecies. In this study, we constructed genomes of a male SED and a male Burmese Eld’s deer (BED), and used genome-wide single nucleotide polymorphisms to evaluate the genetic purity and the inbreeding status of 35 SED and 49 BED with limited pedigree information. The results show that these subspecies diverged approximately 1.26 million years ago. All SED were found to be purebred. A low proportion of admixed SED genetic material was observed in some BED individuals. Six potential breeders from male SED with no genetic relation to any female SED and three purebred male BED with no relation to more than 10 purebred female BED were identified. This study provides valuable insights about Eld’s deer populations and appropriate breeder selection in efforts to repopulate this endangered species while avoiding inbreeding.