Niwetmarin W., Saesian N., Saruengkhanphasit R., Eurtivong C., Thasana N., Ruchirawat S. Metal- and photocatalyst-free approach to visible-light-induced acylation of quinoxalinones. Organic and Biomolecular Chemistry (2024). doi:10.1039/d4ob00630e Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/98351
Title
Metal- and photocatalyst-free approach to visible-light-induced acylation of quinoxalinones
A transition-metal- and photocatalyst-free photochemical reaction was successfully developed for the direct acylation of quinoxalin-2(1H)-ones, which was enabled by the formation of electron donor-acceptor (EDA) complexes. The use of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as the electron donor allows efficient and operationally simple access to a series of C3-aroylated and acylated quinoxalin-2(1H)-ones with moderate to good yields.
