Global Hospitalization Trends for Crohn's Disease and Ulcerative Colitis in the 21st Century: A Systematic Review With Temporal Analyses
Issued Date
2022-01-01
Resource Type
ISSN
15423565
eISSN
15427714
Scopus ID
2-s2.0-85138642703
Pubmed ID
35863682
Journal Title
Clinical Gastroenterology and Hepatology
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical Gastroenterology and Hepatology (2022)
Suggested Citation
Buie M.J., Quan J., Windsor J.W., Coward S., Hansen T.M., King J.A., Kotze P.G., Gearry R.B., Ng S.C., Mak J.W.Y., Abreu M.T., Rubin D.T., Bernstein C.N., Banerjee R., Yamamoto-Furusho J.K., Panaccione R., Seow C.H., Ma C., Underwood F.E., Ahuja V., Panaccione N., Shaheen A.A., Holroyd-Leduc J., Kaplan G.G., Balderramo D., Chong V.H., Juliao-Baños F., Dutta U., Simadibrata M., Kaibullayeva J., Sun Y., Hilmi I., Raja Ali R.A., Paudel M.S., Altuwaijri M., Hartono J.L., Wei S.C., Limsrivilai J., El Ouali S., Vergara B.I., Dao V.H., Kelly P., Hodges P., Miao Y., Li M. Global Hospitalization Trends for Crohn's Disease and Ulcerative Colitis in the 21st Century: A Systematic Review With Temporal Analyses. Clinical Gastroenterology and Hepatology (2022). doi:10.1016/j.cgh.2022.06.030 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/87409
Title
Global Hospitalization Trends for Crohn's Disease and Ulcerative Colitis in the 21st Century: A Systematic Review With Temporal Analyses
Author(s)
Buie M.J.
Quan J.
Windsor J.W.
Coward S.
Hansen T.M.
King J.A.
Kotze P.G.
Gearry R.B.
Ng S.C.
Mak J.W.Y.
Abreu M.T.
Rubin D.T.
Bernstein C.N.
Banerjee R.
Yamamoto-Furusho J.K.
Panaccione R.
Seow C.H.
Ma C.
Underwood F.E.
Ahuja V.
Panaccione N.
Shaheen A.A.
Holroyd-Leduc J.
Kaplan G.G.
Balderramo D.
Chong V.H.
Juliao-Baños F.
Dutta U.
Simadibrata M.
Kaibullayeva J.
Sun Y.
Hilmi I.
Raja Ali R.A.
Paudel M.S.
Altuwaijri M.
Hartono J.L.
Wei S.C.
Limsrivilai J.
El Ouali S.
Vergara B.I.
Dao V.H.
Kelly P.
Hodges P.
Miao Y.
Li M.
Quan J.
Windsor J.W.
Coward S.
Hansen T.M.
King J.A.
Kotze P.G.
Gearry R.B.
Ng S.C.
Mak J.W.Y.
Abreu M.T.
Rubin D.T.
Bernstein C.N.
Banerjee R.
Yamamoto-Furusho J.K.
Panaccione R.
Seow C.H.
Ma C.
Underwood F.E.
Ahuja V.
Panaccione N.
Shaheen A.A.
Holroyd-Leduc J.
Kaplan G.G.
Balderramo D.
Chong V.H.
Juliao-Baños F.
Dutta U.
Simadibrata M.
Kaibullayeva J.
Sun Y.
Hilmi I.
Raja Ali R.A.
Paudel M.S.
Altuwaijri M.
Hartono J.L.
Wei S.C.
Limsrivilai J.
El Ouali S.
Vergara B.I.
Dao V.H.
Kelly P.
Hodges P.
Miao Y.
Li M.
Author's Affiliation
Siriraj Hospital
Cleveland Clinic Abu Dhabi
Kazakh National Medical University
Alberta Health Services
National Taiwan University Hospital
University of Zambia School of Medicine
Raja Isteri Pengiran Anak Saleha Hospital
Hanoi Medical University
Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo
Hospital Pablo Tobon Uribe
Universidad Nacional Autónoma de México
College of Medicine
The University of Chicago
University of Miami
Universiti Malaya
NUS Yong Loo Lin School of Medicine
Barts and The London School of Medicine and Dentistry
Pontifícia Universidade Católica do Paraná
Asian Institute of Gastroenterology India
Kunming Medical University
Hospital Privado Centro Medico de Cordoba
Max Rady College of Medicine, University of Manitoba
All India Institute of Medical Sciences, New Delhi
Chinese University of Hong Kong
University of Calgary
University of Otago, Christchurch
Faculty of Medicine, UKM
Cumming School of Medicine
Postgraduate Institute of Medical Education & Research, Chandigarh
Yunnan Province Clinical Research Center for Digestive Diseases
National Academy of Medical Sciences
Dependiente del Centro de Asistencia del Sindicato Médico del Uruguay
Cleveland Clinic Abu Dhabi
Kazakh National Medical University
Alberta Health Services
National Taiwan University Hospital
University of Zambia School of Medicine
Raja Isteri Pengiran Anak Saleha Hospital
Hanoi Medical University
Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo
Hospital Pablo Tobon Uribe
Universidad Nacional Autónoma de México
College of Medicine
The University of Chicago
University of Miami
Universiti Malaya
NUS Yong Loo Lin School of Medicine
Barts and The London School of Medicine and Dentistry
Pontifícia Universidade Católica do Paraná
Asian Institute of Gastroenterology India
Kunming Medical University
Hospital Privado Centro Medico de Cordoba
Max Rady College of Medicine, University of Manitoba
All India Institute of Medical Sciences, New Delhi
Chinese University of Hong Kong
University of Calgary
University of Otago, Christchurch
Faculty of Medicine, UKM
Cumming School of Medicine
Postgraduate Institute of Medical Education & Research, Chandigarh
Yunnan Province Clinical Research Center for Digestive Diseases
National Academy of Medical Sciences
Dependiente del Centro de Asistencia del Sindicato Médico del Uruguay
Other Contributor(s)
Abstract
Background & Aims: The evolving epidemiologic patterns of inflammatory bowel disease (IBD) throughout the world, in conjunction with advances in therapeutic treatments, may influence hospitalization rates of IBD. We performed a systematic review with temporal analysis of hospitalization rates for IBD across the world in the 21st century. Methods: We systematically reviewed Medline and Embase for population-based studies reporting hospitalization rates for IBD, Crohn's disease (CD), or ulcerative colitis (UC) in the 21st century. Log-linear models were used to calculate the average annual percentage change (AAPC) with associated 95% confidence intervals (95% CIs). Random-effects meta-analysis pooled country-level AAPCs. Data were stratified by the epidemiologic stage of a region: compounding prevalence (stage 3) in North America, Western Europe, and Oceania vs acceleration of incidence (stage 2) in Asia, Eastern Europe, and Latin America vs emergence (stage 1) in developing countries. Results: Hospitalization rates for a primary diagnosis of IBD were stable in countries in stage 3 (AAPC, −0.13%; 95% CI, −0.72 to 0.97), CD (AAPC, 0.20%; 95% CI, −1.78 to 2.17), and UC (AAPC, 0.02%; 95% CI, −0.91 to 0.94). In contrast, hospitalization rates for a primary diagnosis were increasing in countries in stage 2 for IBD (AAPC, 4.44%; 95% CI, 2.75 to 6.14), CD (AAPC, 8.34%; 95% CI, 4.38 to 12.29), and UC (AAPC, 3.90; 95% CI, 1.29 to 6.52). No population-based studies were available for developing regions in stage 1 (emergence). Conclusions: Hospitalization rates for IBD are stabilizing in countries in stage 3, whereas newly industrialized countries in stage 2 have rapidly increasing hospitalization rates, contributing to an increasing burden on global health care systems.