The association between sarcopenia and functional outcomes after hospital discharge among critically ill surgical patients
Issued Date
2022-07-01
Resource Type
ISSN
10159584
eISSN
02193108
Scopus ID
2-s2.0-85116813526
Pubmed ID
34635417
Journal Title
Asian Journal of Surgery
Volume
45
Issue
7
Start Page
1408
End Page
1413
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asian Journal of Surgery Vol.45 No.7 (2022) , 1408-1413
Suggested Citation
Vongchaiudomchoke W., Sathitkarnmanee B., Thanakiattiwibun C., Jarungjitaree S., Chaiwat O. The association between sarcopenia and functional outcomes after hospital discharge among critically ill surgical patients. Asian Journal of Surgery Vol.45 No.7 (2022) , 1408-1413. 1413. doi:10.1016/j.asjsur.2021.09.012 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85786
Title
The association between sarcopenia and functional outcomes after hospital discharge among critically ill surgical patients
Author's Affiliation
Other Contributor(s)
Abstract
Background: To determine the association between sarcopenia in surgical intensive care unit (SICU) patients and long-term functional outcomes. Method: This prospective, cohort study enrolled patients aged >65 years admitted to SICUs at the tertiary care hospital. Their muscle mass and strength were measured by bioelectrical impedance vector analysis (BIVA) and handgrip-strength or manual-muscle-strength tests. The functional outcomes were evaluated with the Thai version of the Barthel index for activities of daily living (ADL). Results: 120 patients were enrolled. A multivariate analysis identified 3 independent predictors associated with poor functional outcomes (ADL scores ≤70) at one month after hospital discharge including sarcopenia (adjusted odds ratio [aOR]: 3.33; 95% confidence interval [CI]: 1.25–8.87); duration of mechanical ventilation (aOR: 1.19; 95% CI: 1.02–1.38); and length of hospital stay (aOR: 1.05; 95% CI: 1.01–1.10). Cox proportional-hazards regression models found that sarcopenia (adjusted hazard ratio [aHR]: 2.07; 95% CI: 1.02–4.22) and admission severity (aHR: 1.13; 95% CI: 1.04–1.23) were predictors of 120-day mortality. Conclusions: Sarcopenia was an independent predictor of poor functional outcomes at one month after hospital discharge.