Obstructive sleep apnea and non-dipper: epiphenomena or risks of Alzheimer’s disease?: a review from the HOPE Asia Network
Issued Date
2023-01-01
Resource Type
ISSN
09169636
eISSN
13484214
Scopus ID
2-s2.0-85174682371
Journal Title
Hypertension Research
Rights Holder(s)
SCOPUS
Bibliographic Citation
Hypertension Research (2023)
Suggested Citation
Nagai M., Dote K., Park S., Turana Y., Buranakitjaroen P., Cheng H.M., Soenarta A.A., Li Y., Kario K. Obstructive sleep apnea and non-dipper: epiphenomena or risks of Alzheimer’s disease?: a review from the HOPE Asia Network. Hypertension Research (2023). doi:10.1038/s41440-023-01440-6 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/90859
Title
Obstructive sleep apnea and non-dipper: epiphenomena or risks of Alzheimer’s disease?: a review from the HOPE Asia Network
Author's Affiliation
Severance Cardiovascular Hospital
Hiroshima City Asa Citizens Hospital
Siriraj Hospital
Jichi Medical University
National Yang-Ming University Taiwan
Universitas Katolik Indonesia Atma Jaya
Universitas Indonesia
University of Oklahoma Health Sciences Center
Ruijin Hospital
Veterans General Hospital-Taipei
Hiroshima City Asa Citizens Hospital
Siriraj Hospital
Jichi Medical University
National Yang-Ming University Taiwan
Universitas Katolik Indonesia Atma Jaya
Universitas Indonesia
University of Oklahoma Health Sciences Center
Ruijin Hospital
Veterans General Hospital-Taipei
Other Contributor(s)
Abstract
Obstructive sleep apnea (OSA) and associated nocturnal blood pressure (BP) surges is associated with non-dipper. On the other hand, the relationship between neurodegenerative diseases and non-dipper hypertension has been reported. To date, few studies have evaluated the relationships of nocturnal BP dipping patterns and OSA in relation to neurodegenerative diseases, particularly Alzheimer’s disease (AD). This review examines the etiology of the association between OSA and the non-dipper pattern of hypertension and how both are involved in the development of AD. To set the stage for this review, we first focus on the pathophysiology of AD, which is interrelated with sleep apnea and non-dipper through dysregulation of central autonomic network. [Figure not available: see fulltext.].