Long-term outcomes after anal fistula surgery: results from two university hospitals in Thailand
Issued Date
2022-01-01
Resource Type
ISSN
22879714
eISSN
22879722
Scopus ID
2-s2.0-85129531687
Journal Title
Annals of Coloproctology
Volume
38
Issue
2
Start Page
133
End Page
140
Rights Holder(s)
SCOPUS
Bibliographic Citation
Annals of Coloproctology Vol.38 No.2 (2022) , 133-140
Suggested Citation
Chadbunchachai W. Long-term outcomes after anal fistula surgery: results from two university hospitals in Thailand. Annals of Coloproctology Vol.38 No.2 (2022) , 133-140. 140. doi:10.3393/ac.2021.01.06 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86571
Title
Long-term outcomes after anal fistula surgery: results from two university hospitals in Thailand
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Purpose: This study aimed to evaluate long-term outcomes after anal fistula surgery from university hospitals in Thailand. Methods: A prospectively collected database of patients with cryptoglandular anal fistula undergoing surgery from 2011 to 2017 in 2 university hospitals was reviewed. Outcomes were treatment failure (persistent or recurrent fistula), fecal continence status, and chronic postsurgical pain. Results: This study included 247 patients; 178 (72.1%) with new anal fistula and 69 (27.9%) with recurrent fistula. One hundred twenty-one patients (49.0%) had complex fistula; 53 semi-horseshoe (21.5%), 41 high transsphincteric (16.6%), 24 horseshoe (9.7%), and 3 suprasphincteric (1.2%). Ligation of intersphincteric fistula tract (LIFT) was the most common operation performed (n = 88, 35.6%) followed by fistulotomy (n = 79, 32.0%). With a median follow-up of 23 months (interquartile range, 12–45 months), there were 18 persistent fistulas (7.3%) and 33 recurrent fistulae (13.4%)—account-ing for 20.6% overall failure. All recurrence occurred within 24 months postoperatively. Complex fistula was the only significant predictor for recurrent fistula with a hazard ratio of 4.81 (95% confidence interval, 1.82–12.71). There was no significant difference in healing rates of complex fistulas among seton staged fistulotomy (85.0%), endorectal advancement flap (72.7%), and LIFT (65.9%) (P = 0.239). Four patients (1.6%) experienced chronic postsurgical pain. Seventeen patients (6.9%) reported worse fecal continence. Conclusion: Overall failure for anal fistula surgery was 20.6%. Complex fistula was the only predictor for recurrent fistula. At least 2-year period of follow-up is suggested for detecting recurrent diseases and assessing patient-reported outcomes such as chronic pain and continence status.