Vertical dengue transmission complicated with neonatal encephalitis
1
Issued Date
2023-12-30
Resource Type
eISSN
1757790X
Scopus ID
2-s2.0-85181766350
Pubmed ID
38160035
Journal Title
BMJ Case Reports
Volume
16
Issue
12
Rights Holder(s)
SCOPUS
Bibliographic Citation
BMJ Case Reports Vol.16 No.12 (2023)
Suggested Citation
Usama S., Assawawiroonhakarn S., Soonsawad S. Vertical dengue transmission complicated with neonatal encephalitis. BMJ Case Reports Vol.16 No.12 (2023). doi:10.1136/bcr-2023-256476 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/95634
Title
Vertical dengue transmission complicated with neonatal encephalitis
Author(s)
Author's Affiliation
Corresponding Author(s)
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Abstract
Vertical transmission of the dengue virus is rare and infrequently reported in the literature. We report the case of a term newborn presented with high-grade fever, generalised petechial rash and hepatomegaly at the age of 5 days, with a history of dengue fever in the mother at 3 days before delivery. The diagnosis was nearly missed because the infant’s dengue NS1 antigen test was initially negative and subsequently positive. After the convalescent phase, the infant developed a new-onset fever with lethargy and drowsiness. Dengue encephalitis was diagnosed with support from a positive dengue reverse-transcriptase PCR in the cerebrospinal fluid. This report has shown the importance of clinical awareness. Early recognition of congenital dengue and vigilant monitoring will contribute to appropriate early management and decrease neonatal morbidity and mortality.