A comprehensive review of melasma with an emphasis on various treatment options in patients with Fitzpatrick skin types III-V
Issued Date
2018
Copyright Date
2018
Resource Type
Language
eng
File Type
application/pdf
No. of Pages/File Size
xi, 91 leaves : ill.
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thematic Paper (M.Sc. (Medicine))--Mahidol University, 2018
Suggested Citation
Patel, Eesha, 1991- A comprehensive review of melasma with an emphasis on various treatment options in patients with Fitzpatrick skin types III-V. Thematic Paper (M.Sc. (Medicine))--Mahidol University, 2018. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/92310
Title
A comprehensive review of melasma with an emphasis on various treatment options in patients with Fitzpatrick skin types III-V
Author(s)
Advisor(s)
Abstract
Melasma is an acquired, symmetric, hyperpigmentary condition mainly seen on the face. The pathogenesis of this condition is not clearly known but UV radiation exposure, hormonal changes and genetics play key roles in its etiology. It is seen in about 1% of the total general population, predominantly in women of reproductive age, and rarely in the pre-pubescent. Various scales have been developed to grade the severity of the disease and its psychosocial impact on the patient, as well as to aid physicians in determining the efficacy of different treatments. The current treatments of melasma are based on preventing various steps in the melanogenesis pathway, such as melanin synthesis and/or proliferation of melanocytes, and on enhancing melanosome degradation. Therefore, it is important to thoroughly understand the pros and cons of each individual modality of treatment to be able to tailor the best treatment option for the patient. Over the past few years, there have been many studies done on the treatments and outcomes of melasma. The aim of this work is to review the current literature on different treatment options for melasma and to suggest robust, evidence-supported guidelines for treatment.
Description
Medicine (Mahidol University 2018)
Degree Name
Master of Science
Degree Level
Master's degree
Degree Department
Faculty of Medicine Ramathibodi Hospital
Degree Discipline
Medicine
Degree Grantor(s)
Mahidol University