Adult IgE-mediated food allergy is on the rise: A review of phenotypes, pathophysiologic mechanisms, diagnosis, and advances in management
Issued Date
2022-01-01
Resource Type
ISSN
0125877X
eISSN
22288694
Scopus ID
2-s2.0-85147045569
Pubmed ID
36681657
Journal Title
Asian Pacific Journal of Allergy and Immunology
Volume
40
Issue
4
Start Page
308
End Page
320
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asian Pacific Journal of Allergy and Immunology Vol.40 No.4 (2022) , 308-320
Suggested Citation
Unhapipatpong C. Adult IgE-mediated food allergy is on the rise: A review of phenotypes, pathophysiologic mechanisms, diagnosis, and advances in management. Asian Pacific Journal of Allergy and Immunology Vol.40 No.4 (2022) , 308-320. 320. doi:10.12932/ap-101122-1499 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85040
Title
Adult IgE-mediated food allergy is on the rise: A review of phenotypes, pathophysiologic mechanisms, diagnosis, and advances in management
Author(s)
Other Contributor(s)
Abstract
The prevalence of adult food allergies is increasing worldwide. Many aspects of food allergy in adulthood are different from childhood. We review the current evidence on adult food allergy regarding the global prevalence, adult phenotypes, cofactors, diagnostic methods, and management. A high proportion of severe reactions and unique phenotypes in adults have been characterized. Individual comorbidities could be risk factors for severe reactions and complicate the physician’s diagnosis as various conditions can mimic food allergies. Many cofactors affect the eliciting threshold of reaction, affecting whether a reaction occurs and its severity. Large and complex meals, various food allergens, and contaminants increase diagnostic difficulties. An action plan should be devised to add a framework for national policies, thereby lessening the biophysical and health-related quality of life impacts of food allergy. Research into novel treatments is ongoing.