Posterior Cranial Decompression in ERF-Mutated Multisuture Craniosynostosis
Issued Date
2026-01-21
Resource Type
ISSN
10492275
eISSN
15363732
Scopus ID
2-s2.0-105035844594
Journal Title
Journal of Craniofacial Surgery
Volume
Publish Ahead of Print
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Craniofacial Surgery Vol.Publish Ahead of Print (2026)
Suggested Citation
Chaisrisawadisuk S., Sathienkijkanchai A., Khampalikit I., Moore M.H. Posterior Cranial Decompression in ERF-Mutated Multisuture Craniosynostosis. Journal of Craniofacial Surgery Vol.Publish Ahead of Print (2026). doi:10.1097/SCS.0000000000012457 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/116388
Title
Posterior Cranial Decompression in ERF-Mutated Multisuture Craniosynostosis
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Multisutural craniosynostosis, involving premature fusion of cranial sutures, leads to abnormal skull shape and elevated intracranial pressure (ICP), threatening neurodevelopment. This case report describes a 6-day-old infant with multisutural craniosynostosis associated with an ERF gene mutation. Imaging confirmed elevated ICP. At 2 months, posterior cranial and foramen magnum decompression effectively reduced ICP, deferring fronto-orbital advancement. By age 2, the child had achieved normal developmental milestones with stable cranial morphology and no Chiari I malformation. Early posterior decompression is a viable first-line intervention for syndromic craniosynostosis, promoting natural bone reformation and reducing secondary surgeries. Multidisciplinary management is essential.