Mushroom β-Glucan Recovered from Antler-Type Fruiting Body of Ganoderma lucidum by Enzymatic Process and Its Potential Biological Activities for Cosmeceutical Applications
Issued Date
2022-10-01
Resource Type
eISSN
20734360
Scopus ID
2-s2.0-85139859119
Journal Title
Polymers
Volume
14
Issue
19
Rights Holder(s)
SCOPUS
Bibliographic Citation
Polymers Vol.14 No.19 (2022)
Suggested Citation
Vaithanomsat P., Boonlum N., Chaiyana W., Tima S., Anuchapreeda S., Trakunjae C., Apiwatanapiwat W., Janchai P., Boondaeng A., Nimitkeatkai H., Jarerat A. Mushroom β-Glucan Recovered from Antler-Type Fruiting Body of Ganoderma lucidum by Enzymatic Process and Its Potential Biological Activities for Cosmeceutical Applications. Polymers Vol.14 No.19 (2022). doi:10.3390/polym14194202 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/85073
Title
Mushroom β-Glucan Recovered from Antler-Type Fruiting Body of Ganoderma lucidum by Enzymatic Process and Its Potential Biological Activities for Cosmeceutical Applications
Author's Affiliation
Other Contributor(s)
Abstract
Mushrooms are incredibly valuable macro fungi that are an important and integral part of the ecosystem. In addition to being used as cuisine, mushrooms have been used for medicinal purposes for many centuries. This research applied a process for recovering β-glucan (BG) from the antler-type fruiting body of Ganoderma lucidum as well as tested the biological activities related to cosmeceutical applications. The characterization of complex structure was performed by fourier-transform infrared (FTIR) and nuclear magnetic resonance (MNR) spectroscopies. The obtained extract contained 40.57% BG and 7.47% protein, with the detectable bioactivities of anti-tyrosinase and antioxidation. Consequently, it showed the activity that can be used to whiten the skin by reducing or inhibiting the process of skin pigmentation. The BG also showed moderate activities of anti-collagenase, anti-elastase, and anti-hyaluronidase. The test by the HET-CAM confirmed no skin irritation of the complex extract. Based on human peripheral blood mononuclear cell (PBMC) test, the BG had no significant inhibiting effect on cell viability. In addition, the obtained BG had functional properties higher than commercially available BG, especially oil-binding capacity. These findings provided new insights into the potential application of G. lucidum BG as a polymeric material in the cosmeceutical industries.