Macular pigment optical density in a Thai sample
Issued Date
2022-01-01
Resource Type
ISSN
17469899
eISSN
17469902
Scopus ID
2-s2.0-85131678095
Journal Title
Expert Review of Ophthalmology
Volume
17
Issue
2
Start Page
153
End Page
160
Rights Holder(s)
SCOPUS
Bibliographic Citation
Expert Review of Ophthalmology Vol.17 No.2 (2022) , 153-160
Suggested Citation
Sae-Lao W., Wunjuntuk K., Techakriengkrai T., Sirichakwal P.P., Yaisawang S., Kom-on S. Macular pigment optical density in a Thai sample. Expert Review of Ophthalmology Vol.17 No.2 (2022) , 153-160. 160. doi:10.1080/17469899.2022.2085558 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/84636
Title
Macular pigment optical density in a Thai sample
Other Contributor(s)
Abstract
Background: The aim of this study was to determine macular pigment optical density (MPOD) and identify factors that correlate with its level in Thai subjects. Research design and methods: This research was a cross-sectional study. Two hundred and forty eyes of 120 participants with healthy eyes underwent MPOD measurement using VISUCAM 500. Demographic and medical data were collected. Pearson’s correlation coefficient analyzed the relationship between the sum of optical densities (MPOD volume) and various factors. MPOD and its influencing factors were analyzed by stepwise multiple regression. Results: The mean age of the participants was 50.7 ± 7.5 years. The mean MPOD was 0.102 ± 0.023 density units. The factors age (r = 0.261, p < 0.01), female gender (r = 0.191, p < 0.05), and consumption of lutein and zeaxanthin (L/Z) supplement (r = 0.168, p < 0.05) were positively associated with MPOD volume. In contrast, normal blood pressure (r =–0.182, p < 0.05) was negatively associated with MPOD volume. No relationship with smoking, body mass index, lipid profile, and family history of AMD on MPOD values was observed in this study. Conclusions: Age, gender and consumption of L/Z supplement were found to be significant predictors of MPOD in Thai subjects.