Synergistic Repellent and Irritant Effects of a Mixture of β-Caryophyllene Oxide and Vetiver Oil against Mosquito Vectors
Issued Date
2023-09-01
Resource Type
eISSN
20754450
Scopus ID
2-s2.0-85172266418
Journal Title
Insects
Volume
14
Issue
9
Rights Holder(s)
SCOPUS
Bibliographic Citation
Insects Vol.14 No.9 (2023)
Suggested Citation
Nararak J., Sanguanpong U., Sukkanon C., Manguin S., Chareonviriyaphap T. Synergistic Repellent and Irritant Effects of a Mixture of β-Caryophyllene Oxide and Vetiver Oil against Mosquito Vectors. Insects Vol.14 No.9 (2023). doi:10.3390/insects14090773 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/90280
Title
Synergistic Repellent and Irritant Effects of a Mixture of β-Caryophyllene Oxide and Vetiver Oil against Mosquito Vectors
Other Contributor(s)
Abstract
Repellents play a major role in reducing the risk of mosquito-borne diseases by preventing mosquito bites. The present study evaluated the mosquito-repellent activity of β-caryophyllene oxide 1% (BCO), vetiver oil 2.5% (VO), and their binary mixtures (BCO + VO (1:1), BCO + VO (2:1), BCO + VO (1:2)) against four laboratory-colonized mosquito species, Aedes aegypti (L.), Aedes albopictus (Skuse), Anopheles minimus Theobald, and Culex quinquefasciatus Say, using an excito-repellency assay system. In general, the compound mixtures produced a much stronger response in the mosquitoes than single compounds, regardless of the test conditions or species. The greatest synergetic effect was achieved with the combination of BCO + VO (1:2) in both contact and noncontact trials with An. minimus (74.07–78.18%) and Cx. quinquefasciatus (55.36–83.64%). Knockdown responses to the binary mixture of BCO + VO were observed for Ae. albopictus, An. minimus, and Cx. quinquefasciatus, in the range of 18.18–33.33%. The synergistic repellent activity of BCO and VO used in this study may support increased opportunities to develop safer alternatives to synthetic repellents for personal protection against mosquitoes.