Revisiting Fruit Allergy: Prevalence across the Globe, Diagnosis, and Current Management
Issued Date
2023-11-01
Resource Type
eISSN
23048158
Scopus ID
2-s2.0-85178376213
Journal Title
Foods
Volume
12
Issue
22
Rights Holder(s)
SCOPUS
Bibliographic Citation
Foods Vol.12 No.22 (2023)
Suggested Citation
Krikeerati T., Rodsaward P., Nawiboonwong J., Pinyopornpanish K., Phusawang S., Sompornrattanaphan M. Revisiting Fruit Allergy: Prevalence across the Globe, Diagnosis, and Current Management. Foods Vol.12 No.22 (2023). doi:10.3390/foods12224083 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/91402
Title
Revisiting Fruit Allergy: Prevalence across the Globe, Diagnosis, and Current Management
Other Contributor(s)
Abstract
Fruit allergies manifest with a diverse array of clinical presentations, ranging from localized contact allergies and oral allergy syndrome to the potential for severe systemic reactions including anaphylaxis. The scope of population-level prevalence studies remains limited, largely derived from single-center or hospital-based investigations. In this comprehensive review, we conducted a systematic literature search spanning the years 2009 to 2023, with full acknowledgment of potential analytical biases, to provide a global overview of fruit allergy prevalence. The primary mechanistic underpinning of fruit allergies stems from cross-reactivity between aeroallergens and food allergens, a consequence of structurally similar epitopes—a phenomenon recognized as pollen food allergy syndrome (PFAS). In the era of molecular allergology, numerous studies have dissected allergen components with substantial clinical relevance. Within this review, we explore important allergenic molecules found in plant-based foods, scrutinize pertinent cross-reactivity patterns, and offer insights into management recommendations. Additionally, we compare guideline recommendations to enhance clinical understanding and inform decision making.